South West Cleft Unit, Frenchay Hospital, Frenchay, Bristol BS16 1LE, United Kingdom.
J Plast Reconstr Aesthet Surg. 2013 Apr;66(4):506-12. doi: 10.1016/j.bjps.2012.12.001. Epub 2013 Jan 22.
Comparison of nasal asymmetry between unilateral cleft lip and palate (UCLP) patients with and without nasal correction at primary repair. Assessment of the value of Symnose as a routine research tool.
75 ten-year-old UCLP patients who underwent primary lip repair by one of two techniques: classical Millard with primary nasal correction (n = 30) or modified Millard without nasal correction (n = 45). Control group of ten-year-old school children (n = 45).
Nasal asymmetry of participants was measured from facial photographs taken in two views: frontal and basal. The Symnose computer program was used to calculate asymmetry for three parameters: front perimeter (FP), base perimeter (BP) and nostrils (N). Total asymmetry was also calculated. Each image was traced on three separate occasions and a mean of the three measurements was calculated.
BP, N and total asymmetry were significantly greater in UCLP patients without nasal correction compared to both controls and patients with correction (BP = 12.73% v 4.90% v 6.75%, N = 47.73% v 15.83% v 30.75%, total = 81.87% v 46.43% v 54.68%, p ≤ 0.001). FP asymmetry was significantly greater in controls than all UCLP patients (22.87% v. 18.18% and 15.07%, p = 0.001 and p = 0.008). BP measurements have a higher degree of repeatability than FP and N (Coefficient of repeatability = 5.99, 17.02 and 16.47, respectively).
Primary nasal correction produces greater nasal symmetry during childhood from the basal view. Symnose is a simple method of objectively measuring asymmetry in UCLP, however improvements are required before it can be considered a useful research tool.
比较单侧唇裂腭裂(UCLP)患者在初次修复时接受和未接受鼻矫正的鼻不对称情况。评估 Symnose 作为常规研究工具的价值。
75 名 10 岁唇裂腭裂患者,由两位医生分别采用两种技术行初次唇修复术:经典 Millard 术式并同期行鼻矫正(n=30)或改良 Millard 术式不做同期鼻矫正(n=45)。另选 10 岁正常儿童 45 名为对照组。
采用正面和基底位两种面像拍摄法测量患者的鼻不对称。使用 Symnose 计算机程序计算三个参数的不对称性:前周长(FP)、基底周长(BP)和鼻孔(N)。还计算了总不对称性。每个图像分别进行三次追踪,并计算三次测量的平均值。
未行同期鼻矫正的 UCLP 患者的 BP、N 和总不对称性明显大于对照组和行同期矫正的患者(BP=12.73%比 4.90%比 6.75%,N=47.73%比 15.83%比 30.75%,总不对称=81.87%比 46.43%比 54.68%,p≤0.001)。对照组的 FP 不对称性明显大于所有 UCLP 患者(22.87%比 18.18%和 15.07%,p=0.001 和 p=0.008)。BP 测量的重复性高于 FP 和 N(可重复性系数分别为 5.99、17.02 和 16.47)。
从基底位看,初次鼻矫正术可在儿童期产生更大的鼻部对称性。Symnose 是一种简单的 UCLP 客观测量不对称的方法,但在将其作为有用的研究工具之前,还需要进一步改进。