Bugaighis I, Mattick C R, Tiddeman B, Hobson R
Department of Orthodontic, Faculty of Dentistry, Benghazi University, Benghazi, Libya.
Orthod Craniofac Res. 2014 Feb;17(1):27-37. doi: 10.1111/ocr.12026. Epub 2013 Jul 15.
To explore three-dimensional (3D) facial asymmetry differences in operated children with oral clefts and to compare the results with a control group.
The sample comprised one hundred and three 8- to 12-year-old children: 40 with unilateral cleft lip and palate (UCLP); 23 with unilateral cleft lip and alveolus (UCLA); 19 with bilateral cleft lip and palate (BCLP); 21 with cleft palate (CP) and 80 sex- and age-matched controls living in the North East of England.
3D stereophotogrammetric facial scans were recorded for each participant at rest. Thirty-nine landmarks were recorded for each scan. The x, y and z coordinates for each landmark were extracted. Kruskal-Wallis and Mann-Whitney tests were conducted to identify 3D landmark asymmetry differences between the groups.
Statistically significant differences were observed between all the groups. The UCLP and UCLA patients displayed the greatest asymmetry, followed by the BCLP group. The CP group was the least asymmetric among the cleft groups. Asymmetry was present to a lesser extent in the control group.
Shape analysis indicates the possible differences in the aetiology and growth pattern of the CP group compared to UCLA or UCLP and BCLP groups.
探讨唇腭裂手术患儿的三维面部不对称差异，并与对照组结果进行比较。
样本包括103名8至12岁儿童：40名单侧唇腭裂（UCLP）患儿；23名单侧唇裂合并牙槽突裂（UCLA）患儿；19名双侧唇腭裂（BCLP）患儿；21名腭裂（CP）患儿，以及80名居住在英格兰东北部、年龄和性别匹配的对照组儿童。
为每位参与者在静息状态下进行三维立体摄影面部扫描。每次扫描记录39个标志点。提取每个标志点的x、y和z坐标。进行Kruskal-Wallis检验和Mann-Whitney检验，以确定各组之间三维标志点不对称差异。
所有组之间均观察到具有统计学意义的差异。UCLP和UCLA患者表现出最大的不对称性，其次是BCLP组。CP组在腭裂组中不对称程度最小。对照组的不对称程度较小。
形状分析表明，与UCLA、UCLP和BCLP组相比，CP组在病因和生长模式上可能存在差异。
