Amirzadeh Ali, Klaustermeyer William
Allergy and Immunology Group, Walla Walla Clinic, 55 W. Tietan St., Walla Walla, WA 99362, USA.
Ear Nose Throat J. 2013 Jan;92(1):E4-5. doi: 10.1177/014556131309200116.
In most cases, the diagnostic evaluation of angioedema is challenging, as there are many possible etiologies. We report a case of an infiltrating lipoma of the tongue that masqueraded as angioedema. The patient, a 68-year-old man, presented with tongue swelling that had followed a waxing and waning course over a 6-month period. Physical examination showed a diffusely enlarged tongue with no discrete mass. A laboratory evaluation for angioedema was unremarkable. After the patient's condition did not respond to treatment with antihistamines and oral prednisone, a further workup was initiated. Magnetic resonance imaging of the neck and computed tomography of the oral cavity revealed only diffuse enlargement of the tongue. The patient underwent a tongue biopsy, which identified the cause of the swelling to be an infiltrating lipoma of the tongue. Clinicians should be aware that other causes of tongue swelling may mimic angioedema.
在大多数情况下，血管性水肿的诊断评估具有挑战性，因为其病因众多。我们报告一例伪装成血管性水肿的舌部浸润性脂肪瘤病例。患者为一名68岁男性，出现舌部肿胀，病程6个月，呈反复消长。体格检查显示舌体弥漫性肿大，未触及肿物。血管性水肿的实验室检查无异常。患者对抗组胺药和口服泼尼松治疗无反应后，进一步检查开始。颈部磁共振成像和口腔计算机断层扫描仅显示舌体弥漫性肿大。患者接受了舌部活检，结果确定肿胀原因是舌部浸润性脂肪瘤。临床医生应意识到，舌部肿胀的其他原因可能会伪装成血管性水肿。
