Wang Xiusong, Zhao Ke, Wang Dong, Adams Wendy, Fu Yu, Sun Huaying, Liu Xiaofen, Yu Hualin, Ma Yuanye
Laboratory of Primate Neuroscience Research, Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China.
Bioelectromagnetics. 2013 May;34(4):275-84. doi: 10.1002/bem.21775. Epub 2013 Jan 25.
Adolescence is a critical developmental stage during which substantial remodeling occurs in brain areas involved in emotional and learning processes. Although a robust literature on the biological effects of extremely low frequency magnetic fields (ELF-MFs) has been documented, data on the effects of ELF-MF exposure during this period on cognitive functions remain scarce. In this study, early adolescent male mice were exposed from postnatal day (P) 23-35 to a 50 Hz MF at 2 mT for 60 min/day. On P36-45, the potential effects of the MF exposure on spatial memory performance were examined using the Y-maze and Morris water maze tasks. The results showed that the MF exposure did not affect Y-maze performance but improved spatial learning acquisition and memory retention in the water maze task under the present experimental conditions.
青春期是一个关键的发育阶段，在此期间，参与情绪和学习过程的脑区会发生大量重塑。尽管已经有大量关于极低频磁场（ELF-MFs）生物学效应的文献记载，但关于这一时期暴露于ELF-MF对认知功能影响的数据仍然稀少。在本研究中，青春期早期雄性小鼠从出生后第（P）23天至35天每天暴露于2 mT的50 Hz磁场中60分钟。在P36 - 45天，使用Y迷宫和莫里斯水迷宫任务检查磁场暴露对空间记忆表现的潜在影响。结果表明，在当前实验条件下，磁场暴露不影响Y迷宫表现，但改善了水迷宫任务中的空间学习获得和记忆保持。
