Silverman S, Gorsky M
Division of Oral Medicine, School of Dentistry, University of California, San Francisco 94143.
J Am Dent Assoc. 1990 May;120(5):495-9. doi: 10.14219/jada.archive.1990.0082.
The number of new oral cancers diagnosed in the United States increases each year, with 31,000 cases reported in 1989. Unfortunately, in spite of advances in surgery, radiation, and chemotherapy, only about 50% of patients with oral cancer will survive their disease. During the past 12 years in which information is available, there have been no decided changes in age (mean 63), gender (males slightly outnumber females two to one), or sites (tongue most common). The lip is the only oral site showing an interval-decreased incidence. There is a slight trend toward an improvement in earlier detection; however, about two-thirds of all oral cancers are advanced (Stage III and IV) at the time of diagnosis.
在美国，每年新诊断出的口腔癌病例数量都在增加，1989年报告了31000例。不幸的是，尽管在手术、放疗和化疗方面取得了进展，但只有约50%的口腔癌患者能战胜疾病存活下来。在有数据可查的过去12年里，患者的年龄（平均63岁）、性别（男性略多于女性，比例为二比一）或发病部位（最常见于舌头）均没有明显变化。嘴唇是唯一一个发病率呈阶段性下降的口腔部位。早期检测方面有略微的改善趋势；然而，所有口腔癌病例中约有三分之二在诊断时已处于晚期（III期和IV期）。
