Panigassi Ana Paula Nascimento, Araujo Júnior Edward, Nardozza Luciano Marcondes Machado, Moron Antonio Fernandes, Pares David Baptista da Silva
Department of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo - SP, Brazil.
J Matern Fetal Neonatal Med. 2013 Jul;26(11):1116-20. doi: 10.3109/14767058.2013.771164. Epub 2013 Feb 27.
To evaluate the influence of different races over the measurement of the frontomaxillary facial angle between 11 and 13 + 6 weeks of pregnancy in a Brazilian population.
A cross-sectional study was conducted with 332 healthy pregnant women, with a crown-rump length (CRL) between 47 and 84 mm. Such measurements were taken abdominally, using the mid-sagittal plane, and the angle was measured by tracing a line over the palate and a line from the anterosuperior maxillary angle all the way to the external part of the forehead. As for the reference intervals, a simple linear regression between the frontomaxillary facial angle and the CRL was used, as well as Pearson's correlation coefficient (r). To evaluate the difference between races, a variance analysis was used (ANOVA). To calculate reproducibility, the intraclass correlation coefficient (ICC) was used.
The means for the fetal frontomaxillary facial angle in white, black and mixed races were 81.8 ± 6.6; 82.2 ± 6.1 and 81.4 ± 6.2 mm, respectively. There was no statistical difference between races (p = 0.713). A decreasing correlation between the frontomaxillary facial angle and the CRL was observed for the black (r = -0.450) and mixed (r = -0.212) races. Excellent intraobserver reproducibility was observed, as well as a satisfactory interobserver reproducibility, with ICC of 0.858 and 0.605, respectively.
There were no significative statistical differences in the measurement of the fetal frontomaxillary facial angle between 11 and 13 + 6 weeks of pregnancy in the different races in a Brazilian population.
评估不同种族对巴西人群妊娠11至13⁺⁶周时额上颌面部角测量值的影响。
对332名健康孕妇进行横断面研究，其头臀长（CRL）在47至84毫米之间。这些测量通过腹部进行，使用正中矢状面，该角度通过在上腭画一条线以及从上颌前上角一直到前额外部画一条线来测量。至于参考区间，使用额上颌面部角与CRL之间的简单线性回归以及皮尔逊相关系数（r）。为评估种族之间的差异，采用方差分析（ANOVA）。为计算可重复性，使用组内相关系数（ICC）。
白人、黑人和混血种族胎儿额上颌面部角的平均值分别为81.8±6.6；82.2±6.1和81.4±6.2毫米。种族之间无统计学差异（p = 0.713）。观察到黑种人（r = -0.450）和混血种人（r = -0.212）的额上颌面部角与CRL之间呈递减相关性。观察到观察者内重复性极佳，观察者间重复性也令人满意，ICC分别为0.858和0.605。
在巴西人群中，不同种族妊娠11至13⁺⁶周时胎儿额上颌面部角的测量值无显著统计学差异。
