多齿蹄盖蕨（Doll.）Ching 中提取的多糖级分的抗氧化活性。
Antioxidant activity of polysaccharide fractions extracted from Athyrium multidentatum (Doll.) Ching.
机构信息
Department of Pharmacy and Biological Sciences, Weifang Medical University, Weifang 261053, PR China.
出版信息
Int J Biol Macromol. 2013 May;56:1-5. doi: 10.1016/j.ijbiomac.2013.01.023. Epub 2013 Jan 25.
Crude polysaccharides were extracted from Athyrium multidentatum (Doll.) Ching (AMC) rhizome and fractionated by DEAE-Cellulose 52 ion-exchange column chromatography. Two polysaccharide fractions (F1 and F2) were obtained and had their antioxidant activities investigated employing various established in vitro systems. All fractions possessed considerable antioxidant activity. Chemical analysis suggested that F1 and F2 were neutral heteropolysaccharide in which glucose was the major component. Available data suggested that the molecular weight and sulfate content played very important roles on antioxidant activity. Our results indicated that the polysaccharides may contribute to the medicinal functions of AMC.
从蹄盖蕨科阴地蕨属植物多足阴地蕨（Athyrium multidentatum (Doll.) Ching）的根茎中提取粗多糖，并通过 DEAE-纤维素 52 离子交换柱层析进行分离。得到了两个多糖级分（F1 和 F2），并采用各种已建立的体外系统研究了它们的抗氧化活性。所有级分均具有相当的抗氧化活性。化学分析表明，F1 和 F2 是中性杂多糖，其中葡萄糖是主要成分。现有数据表明，分子量和硫酸根含量对抗氧化活性起着非常重要的作用。我们的结果表明，多糖可能是多足阴地蕨药用功能的物质基础。
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