[Baroreceptor regulation of blood circulation in healthy persons and in patients with hypertension].

Carotid sinus baroreceptor stimulation by generating subatmospheric pressure in a special neck chamber was used to examine the hemodynamic baroregulation in males divided into 4 groups: (1) healthy subjects; (2) patients with Stages IB to IIA hypertensive disease; (3) those with Stage IIB hypertension; (4) those with malignant hypertension. In Group 2, the patients had a lower ability of carotid baroreflexes to damp elevated systolic pressure whereas in Group 3 there was baroreflex readjustment and effective vasomotor control was increased, which appeared as more pronounced lowering of blood pressure elevations. The patients with malignant hypertension showed a decreased effective baroreflex control of circulation, which might be one of the factors causing that course of the disease.