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1996-2011 年孟加拉国达卡一家腹泻病医院的非伤寒沙门氏菌性胃肠炎。

Non-typhoidal Salmonella gastroenteritis at a diarrheal hospital in Dhaka, Bangladesh, 1996-2011.

机构信息

Centre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh.

出版信息

Am J Trop Med Hyg. 2013 Apr;88(4):661-9. doi: 10.4269/ajtmh.12-0672. Epub 2013 Jan 28.

Abstract

Data on non-typhoidal Salmonella (NTS) infection in South Asia are limited. We used data gathered prospectively from 1996 to 2011 as part of a hospital surveillance system in Dhaka, Bangladesh, to identify diarrheal patients with NTS isolated from stool. NTS was isolated in 1.3% (468 of 37,439) of diarrheal patients; 47% of total cases of NTS were in children < 5 years of age, although older adults (≥ 60 years) had the highest isolation rates. NTS isolation peaked in the monsoon months of July and August. Over the study period, rates of multidrug resistance decreased, whereas rates of decreased susceptibility to ciprofloxacin increased. Compared with control patients, NTS patients were older and wealthier; however, no differences in type of housing or exposure to animals were found. NTS patients had increased inflammatory cells in stool and required more fluid resuscitation.

摘要

南亚关于非伤寒沙门氏菌(NTS)感染的数据有限。我们使用了 1996 年至 2011 年期间作为孟加拉国达卡医院监测系统的一部分前瞻性收集的数据,以确定从粪便中分离出 NTS 的腹泻患者。NTS 在 1.3%(37439 例腹泻患者中的 468 例)的腹泻患者中分离出来;47%的 NTS 总病例发生在<5 岁的儿童中,尽管老年人(≥60 岁)的分离率最高。NTS 的分离在 7 月和 8 月的季风月份达到高峰。在研究期间,多药耐药率下降,而对环丙沙星的敏感性降低率增加。与对照患者相比,NTS 患者年龄更大、更富裕;然而,在住房类型或接触动物方面没有发现差异。NTS 患者粪便中炎症细胞增多,需要更多的液体复苏。

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