2006-2008 年台湾地区非伤寒型沙门氏菌感染的流行病学、疾病谱和经济负担。
Epidemiology, disease spectrum and economic burden of non-typhoidal Salmonella infections in Taiwan, 2006-2008.
机构信息
Department of Medicine, National Cheng Kung University Medical College, Tainan, Taiwan.
出版信息
Epidemiol Infect. 2012 Dec;140(12):2256-63. doi: 10.1017/S0950268812000088. Epub 2012 Feb 6.
Abstract
The purpose of this study was to understand the seasonal, geographical and clinical characteristics of Taiwanese patients hospitalized for non-typhoidal Salmonella (NTS) infections and their economic burden. Hospital data obtained from the Taiwan National Health Insurance (NHI) database between 2006 and 2008 were analysed. Infants had the highest annual incidence of 525 cases/100 000 person-years. Elderly patients aged >70 years had the highest in-hospital mortality rate (2·6%). Most (82·6%) gastroenteritis occurred in children aged <10 years. Septicaemia, pneumonia, arthritis and osteomyelitis occurred mainly in patients aged >50 years. A median medical cost for NTS-associated hospitalizations was higher for patients with septicaemia than for those with gastroenteritis. Seasonal variation of NTS-associated hospitalizations was correlated with temperature in different areas of Taiwan. In summary, infants had a high incidence of NTS-associated hospitalizations. However, the elderly had a higher in-hospital mortality rate and more invasive NTS infections than children.
摘要
本研究旨在了解台湾非伤寒型沙门氏菌（NTS）感染住院患者的季节性、地理和临床特征及其经济负担。对 2006 年至 2008 年期间从台湾全民健康保险（NHI）数据库中获得的医院数据进行了分析。婴儿的年发病率最高，为 525 例/10 万人年。>70 岁的老年患者住院死亡率最高（2.6%）。大多数（82.6%）肠胃炎发生在<10 岁的儿童中。败血症、肺炎、关节炎和骨髓炎主要发生在>50 岁的患者中。与肠胃炎相比，败血症相关住院治疗的中位医疗费用更高。与 NTS 相关的住院治疗季节性变化与台湾不同地区的温度有关。总之，婴儿 NTS 相关住院治疗的发病率较高。然而，老年人的住院死亡率高于儿童，且侵袭性 NTS 感染也多于儿童。
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