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病毒会立即对宿主上载体的存在做出反应，并形成传播形态。

A virus responds instantly to the presence of the vector on the host and forms transmission morphs.

作者信息

Martinière Alexandre, Bak Aurélie, Macia Jean-Luc, Lautredou Nicole, Gargani Daniel, Doumayrou Juliette, Garzo Elisa, Moreno Aranzazu, Fereres Alberto, Blanc Stéphane, Drucker Martin

机构信息

Virus Insect Plant Laboratory, INRA, Mixed Research Unit 385 , Campus International de Baillarguet , Montpellier , France.

出版信息

Elife. 2013 Jan 22;2:e00183. doi: 10.7554/eLife.00183.

DOI:10.7554/eLife.00183
PMID:23358702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3552618/
Abstract

Many plant and animal viruses are spread by insect vectors. Cauliflower mosaic virus (CaMV) is aphid-transmitted, with the virus being taken up from specialized transmission bodies (TB) formed within infected plant cells. However, the precise events during TB-mediated virus acquisition by aphids are unknown. Here, we show that TBs react instantly to the presence of the vector by ultra-rapid and reversible redistribution of their key components onto microtubules throughout the cell. Enhancing or inhibiting this TB reaction pharmacologically or by using a mutant virus enhanced or inhibited transmission, respectively, confirming its requirement for efficient virus-acquisition. Our results suggest that CaMV can perceive aphid vectors, either directly or indirectly by sharing the host perception. This novel concept in virology, where viruses respond directly or via the host to the outside world, opens new research horizons, that is, investigating the impact of 'perceptive behaviors' on other steps of the infection cycle.DOI:http://dx.doi.org/10.7554/eLife.00183.001.

摘要

许多植物和动物病毒是由昆虫媒介传播的。花椰菜花叶病毒（CaMV）通过蚜虫传播，病毒从受感染植物细胞内形成的特殊传播体（TB）中获取。然而，蚜虫通过TB介导获取病毒的确切过程尚不清楚。在此，我们表明，TB通过其关键成分在整个细胞内微管上的超快速和可逆重新分布，对媒介的存在立即做出反应。通过药理学方法增强或抑制这种TB反应，或使用突变病毒，分别增强或抑制了传播，证实了其对有效获取病毒的必要性。我们的结果表明，CaMV可以直接或通过共享宿主感知间接感知蚜虫媒介。病毒学中的这一新概念，即病毒直接或通过宿主对外部世界做出反应，开辟了新的研究视野，即研究“感知行为”对感染周期其他步骤的影响。DOI:http://dx.doi.org/10.7554/eLife.00183.001

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238e/3552618/ebf4ef21d068/elife00183f011.jpg
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2
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PLoS One. 2011;6(8):e23241. doi: 10.1371/journal.pone.0023241. Epub 2011 Aug 10.
3
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