Suppr超能文献

癌症幸存者诊断后 2 年内重返工作岗位过程中的性别差异:来自大型法国基于人群样本的研究结果。

Sex differences in the return-to-work process of cancer survivors 2 years after diagnosis: results from a large French population-based sample.

机构信息

INSERM UMR 912, Institut Paoli-Calmettes, Marseilles Cedex 9, France.

出版信息

J Clin Oncol. 2013 Apr 1;31(10):1277-84. doi: 10.1200/JCO.2011.38.5401. Epub 2013 Jan 28.

Abstract

PURPOSE

To investigate the effects of clinical, sociodemographic, and occupational factors on time to return to work (RTW) during the 2 years after cancer diagnosis and to analyze whether sex differences exist.

PATIENTS AND METHODS

This study was based on a French national cross-sectional survey involving 4,270 cancer survivors. Time to RTW was estimated through the duration of sick leave of 801 cancer survivors younger than 58 years who were employed during the 2-year survey. Multivariate analysis of the RTW after sick leave was performed using a Weibull accelerated failure time model.

RESULTS

We found some sex differences in the RTW process. Older men returned to work more slowly than older women (P = .013), whereas married men returned to work much faster than married women (P = .019). Duration dependence was also sex-specific. In men, the time spent on sick leave was independent of the probability of returning to work, whereas in women, this duration dependence was positive (P < .001). For both men and women, clinical factors including chemotherapy, adverse effects, and cancer severity were found to delay RTW (P = .035, P = .001, and P < .001, respectively). Survivors investing most strongly in their personal lives also delayed their RTW (P = .006), as did those with a permanent work contract (P = .042). The factor found to accelerate RTW was a higher educational level (P = .014).

CONCLUSION

The RTW process 2 years after cancer diagnosis differed between men and women. A better knowledge of this process should help the national implementation of more cost-effective strategies for managing the RTW of cancer survivors.

摘要

目的

研究临床、社会人口学和职业因素对癌症诊断后 2 年内重返工作岗位 (RTW) 的时间的影响,并分析是否存在性别差异。

方法

本研究基于一项涉及 4270 名癌症幸存者的法国全国横断面调查。通过对 801 名年龄小于 58 岁且在 2 年调查期间在职的癌症幸存者的病假时间进行估计,来确定 RTW 时间。使用威布尔加速失效时间模型对病假后的 RTW 进行多变量分析。

结果

我们发现 RTW 过程中存在一些性别差异。年龄较大的男性比年龄较大的女性返回工作岗位的速度较慢(P =.013),而已婚男性比已婚女性返回工作岗位的速度快得多(P =.019)。持续时间依赖性也是特定于性别的。在男性中,病假时间与返回工作的概率无关,而在女性中,这种持续时间依赖性是阳性的(P <.001)。对于男性和女性,包括化疗、副作用和癌症严重程度在内的临床因素都被发现会延迟 RTW(P =.035、P =.001 和 P <.001)。个人生活投入最多的幸存者也会延迟 RTW(P =.006),而那些拥有永久工作合同的幸存者也会延迟 RTW(P =.042)。促进 RTW 的因素是更高的教育水平(P =.014)。

结论

癌症诊断后 2 年内的 RTW 过程在男性和女性之间存在差异。更好地了解这一过程应有助于国家实施更具成本效益的策略,以管理癌症幸存者的 RTW。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验