Thurston Arthritis Research Center, University of North Carolina at Chapel Hill.
J Phys Act Health. 2014 Feb;11(2):285-95. doi: 10.1123/jpah.2011-0307. Epub 2013 Jan 28.
Adults with arthritis can benefit from participation in physical activity and may be assisted by organized programs. The purpose of this study was to evaluate the effectiveness of a 20-week behavioral lifestyle intervention, Active Living Every Day (ALED), for improvements in primary outcomes (physical activity levels, aerobic endurance, function, symptoms).
A 20-week randomized controlled community trial was conducted in 354 adults. Outcomes were assessed at baseline and 20 weeks in the intervention and wait-list control groups. The intervention group was also assessed at 6 and 12 months. Mean outcomes were determined by multilevel regression models in the intervention and control groups at follow-up points.
At 20 weeks, the intervention group significantly increased participation in physical activity, and improved aerobic endurance, and select measures of function while pain, fatigue and stiffness remained status quo. In the intervention group, significant improvements in physical activity at 20 weeks were maintained at 6 and 12 months, and stiffness decreased.
ALED appears to improve participation in physical activity, aerobic endurance, and function without exacerbating disease symptoms in adults with arthritis.
关节炎患者可以从身体活动中受益，并且可能会受益于有组织的项目。本研究的目的是评估为期 20 周的行为生活方式干预（即每天积极生活，ALED）对主要结果（身体活动水平、有氧耐力、功能、症状）的改善效果。
在 354 名成年人中进行了为期 20 周的随机对照社区试验。在干预组和等待名单对照组中，在基线和 20 周时评估了结果。干预组还在 6 个月和 12 个月时进行了评估。在随访点，通过多层次回归模型确定了干预组和对照组的平均结果。
在 20 周时，干预组的身体活动参与度显著增加，有氧耐力和某些功能指标得到改善，而疼痛、疲劳和僵硬则保持不变。在干预组中，20 周时的身体活动显著改善在 6 个月和 12 个月时得到维持，并且僵硬程度有所下降。
ALED 似乎可以改善关节炎患者的身体活动参与度、有氧耐力和功能，而不会使疾病症状恶化。
