无创衍生的呼吸严重程度评分和通气新生儿的氧合指数。

Non-invasively derived respiratory severity score and oxygenation index in ventilated newborn infants.

机构信息

Department of Pediatrics, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio 44109, USA.

出版信息

Pediatr Pulmonol. 2013 Apr;48(4):364-9. doi: 10.1002/ppul.22607. Epub 2013 Jan 28.

DOI:10.1002/ppul.22607

PMID:23359457

Abstract

OBJECTIVE

To evaluate the association between the respiratory severity score (RSS) and oxygenation index (OI) in intubated, mechanically ventilated, newborn infants.

STUDY DESIGN

In a retrospective cohort study (December 2006 to June 2010) medical records of all infants who were admitted to our neonatal intensive care unit (NICU) and required invasive mechanical ventilation were reviewed for patients' demographics, ventilator settings, and arterial blood gas (ABG).

RESULTS

During the study period 2,332 infants were admitted to our NICU, and 425 infants were intubated and had an ABG with a gestational age of 30.5 ± 4.9 weeks and a birth weight of 1,635 ± 923 g (mean ± standard deviation). There was a strong association between RSS and OI in infants with oxygen saturation (SaO2 ) between 88% and 94% (R2 = 0.982, n = 101; P < 0.001).

CONCLUSION

In intubated newborn infants, there is a strong association between RSS and OI at SaO2 between 88% and 94%.

摘要

目的

评估有创机械通气新生儿呼吸严重程度评分（RSS）与氧合指数（OI）的相关性。

研究设计

本回顾性队列研究（2006 年 12 月至 2010 年 6 月）纳入我院新生儿重症监护病房（NICU）中所有需有创机械通气的新生儿患者，分析其人口统计学特征、呼吸机参数和动脉血气（ABG）结果。

结果

研究期间我院 NICU 共收治 2332 例新生儿，其中 425 例行气管插管并进行了 ABG 检查，患儿的胎龄为 30.5±4.9 周，出生体重为 1635±923g（均数±标准差）。在 SaO2 为 88%至 94%的患儿中，RSS 与 OI 之间具有很强的相关性（R2=0.982，n=101；P<0.001）。