Walker Stuart R, Smith Anne
Royal Hobart Hospital, Hobart, Tasmania, Australia.
ANZ J Surg. 2013 Nov;83(11):844-6. doi: 10.1111/ans.12077. Epub 2013 Jan 29.
The aim of this study was to assess the effect of povidone-iodine on the groin wounds of patients undergoing primary varicose vein surgery.
This is a prospective, randomized, blinded, controlled study on patients undergoing primary saphenofemoral ligation. Patients were randomized to a povidone-iodine (Betadine; Pfizer, West Ryde, Australia)-soaked surgical gauze placed in the open wound or a saline-soaked gauze placed in the wound. Patients were then followed up weekly for 6 weeks to observe for signs of wound infection.
Sixty-eight legs in 49 patients were recruited. Thirty-seven groin wounds were randomized to saline and 32 to Betadine. There was a reduced incidence of groin wound infections in those randomized to Betadine (3 versus 1), but this was not statistically significant (P = 0.4).
Although there may be a trend towards a lower wound infection rate when povidone-iodine is use in surgical wounds, this is not significant for varicose vein surgery.
本研究旨在评估聚维酮碘对原发性静脉曲张手术患者腹股沟伤口的影响。
这是一项针对接受原发性大隐静脉高位结扎术患者的前瞻性、随机、双盲、对照研究。患者被随机分为两组，一组使用浸泡过聚维酮碘（碘伏；辉瑞公司，澳大利亚西赖德）的手术纱布置于开放伤口处，另一组使用浸泡过生理盐水的纱布置于伤口处。然后对患者进行为期6周的每周随访，观察伤口感染迹象。
共纳入49例患者的68条腿。37个腹股沟伤口被随机分配至生理盐水组，32个被分配至碘伏组。随机分配至碘伏组的患者腹股沟伤口感染发生率较低（3例对1例），但差异无统计学意义（P = 0.4）。
尽管在手术伤口中使用聚维酮碘时伤口感染率可能有降低趋势，但对于静脉曲张手术而言，这一差异并不显著。
