Sankararaman Senthilkumar, Shah Kinjal, Maddox Kevin, Velayuthan Sujithra, Scott L Keith
Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, USA.
J La State Med Soc. 2012 Sep-Oct;164(5):293-6.
Iron deficiency anemia is the most common cause of anemia in all age groups. Idiopathic pulmonary hemosiderosis is an extremely rare etiology of iron deficiency anemia seen predominantly in the pediatric population. Idiopathic pulmonary hemosiderosis is characterized by the triad of symptoms consisting of iron deficiency anemia, diffuse pulmonary infiltrates, and hemoptysis. The clinical presentation is extremely variable, and all three symptoms may not always be seen. Due to the rarity of the disease and the variability in clinical presentation, diagnosis is usually delayed. Early diagnosis and treatment with corticosteroids prevents further episodes of recurrent alveolar hemorrhage and improves the clinical outcome. Hence, a high index of suspicion is required for the diagnosis of this condition in young patients presenting with severe iron deficiency anemia and diffuse pulmonary infiltrates. We report a toddler with idiopathic pulmonary hemosiderosis whose initial clinical presentation was severe iron deficiency anemia.
缺铁性贫血是所有年龄组中最常见的贫血原因。特发性肺含铁血黄素沉着症是缺铁性贫血的一种极其罕见的病因,主要见于儿童人群。特发性肺含铁血黄素沉着症的特征是由缺铁性贫血、弥漫性肺浸润和咯血组成的三联征症状。临床表现差异极大,并非总是能见到所有三种症状。由于该疾病罕见且临床表现多变,诊断通常会延迟。早期诊断并使用皮质类固醇进行治疗可预防反复肺泡出血的进一步发作,并改善临床结局。因此,对于患有严重缺铁性贫血和弥漫性肺浸润的年轻患者,诊断此病需要高度的怀疑指数。我们报告一名患有特发性肺含铁血黄素沉着症的幼儿,其最初的临床表现为严重缺铁性贫血。