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一名最初表现为缺铁性贫血的儿童特发性肺含铁血黄素沉着症伴严重呼吸窘迫

Severe Respiratory Distress in a Child with Pulmonary Idiopathic Hemosiderosis Initially Presenting with Iron-Deficiency Anemia.

作者信息

Potalivo A, Finessi L, Facondini F, Lupo A, Andreoni C, Giuliani G, Cavicchi C

机构信息

Department of Emergency, Anaesthesia and Intensive Care Section, Infermi Hospital, Viale Luigi Settembrini 2, 47923 Rimini, Italy.

出版信息

Case Rep Pulmonol. 2015;2015:876904. doi: 10.1155/2015/876904. Epub 2015 Nov 8.

Abstract

Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of alveolar hemorrhage in children but should be considered in children with anemia of unknown origin who develop respiratory complications. It is commonly characterized by the triad of recurrent hemoptysis, diffuse parenchymal infiltrates, and iron-deficiency anemia. Pathogenesis is unclear and diagnosis may be difficult along with a variable clinical course. A 6-year-old boy was admitted to the hospital with a severe iron-deficiency anemia, but he later developed severe acute respiratory failure and hemoptysis requiring intubation and mechanical ventilation. The suspicion of IPH led to the use of immunosuppressive therapy with high dose of corticosteroids with rapid improvement in clinical condition and discharge from hospital.

摘要

特发性肺含铁血黄素沉着症(IPH)是儿童肺泡出血的罕见病因,但对于不明原因贫血且出现呼吸并发症的儿童应予以考虑。其常见特征为咯血反复发作、弥漫性实质浸润和缺铁性贫血三联征。发病机制尚不清楚,临床过程多变,诊断可能困难。一名6岁男孩因严重缺铁性贫血入院,但后来发展为严重急性呼吸衰竭和咯血,需要插管和机械通气。怀疑为IPH后,采用高剂量皮质类固醇进行免疫抑制治疗,临床状况迅速改善并出院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18c0/4655028/8e955141102f/CRIPU2015-876904.001.jpg

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