Krause-Utz Annegret, Sobanski Esther, Alm Barbara, Valerius Gabriele, Kleindienst Nikolaus, Bohus Martin, Schmahl Christian
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany.
J Nerv Ment Dis. 2013 Feb;201(2):116-23. doi: 10.1097/NMD.0b013e31827f6462.
Impulsivity is regarded as a key feature in borderline personality disorder (BPD). However, discrepancies in previous research indicate that the role of impulsivity in BPD is not yet fully understood. For example, state-dependent impulsivity in individuals with BPD may be related to co-occurring psychiatric conditions such as attention-deficit/hyperactivity disorder (ADHD) and to emotional states. We assessed self-reports of trait and state impulsivity and response inhibition before and after an experimental stress induction in 15 patients with BPD without ADHD, 15 patients with BPD and ADHD, 15 patients with ADHD, and 15 healthy participants. The patients in both BPD subgroups reported a stress-dependent increase of state impulsivity, which was not observed in the other groups. Response inhibition was impaired in the patients with BPD and ADHD but not in those without ADHD compared with the healthy participants. We suggest that stress levels and co-occurring ADHD should receive attention in future studies on impulsivity in BPD.
冲动性被视为边缘性人格障碍(BPD)的一个关键特征。然而,以往研究中的差异表明,冲动性在BPD中的作用尚未得到充分理解。例如,BPD患者的状态依赖性冲动性可能与共病的精神疾病如注意力缺陷多动障碍(ADHD)以及情绪状态有关。我们评估了15名无ADHD的BPD患者、15名有BPD和ADHD的患者、15名ADHD患者以及15名健康参与者在实验性应激诱导前后的特质和状态冲动性自我报告以及反应抑制情况。两个BPD亚组的患者均报告状态冲动性随应激而增加,其他组未观察到这种情况。与健康参与者相比,有BPD和ADHD的患者反应抑制受损,而无ADHD的患者则未受损。我们建议,在未来关于BPD冲动性的研究中应关注应激水平和共病的ADHD。