Nakayama Yujiro, Horio Hirotoshi, Horiguchi Shinichiro, Hato Tai
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Bunkyo-ku, Tokyo, Japan.
Ann Thorac Cardiovasc Surg. 2014;20(5):410-3. doi: 10.5761/atcs.cr.11.01852. Epub 2013 Jan 31.
Meningiomas are generally benign tumors, but rarely metastasize outside of the central nervous system. A 25-year-old female was admitted to our institute because of an abnormal shadow on her chest x-ray. A computed tomography (CT) scan showed a 3-cm, well- circumscribed mass in the right lower lobe of the lung. We performed thoracotomy and resected three pulmonary tumors at the right lung and diaphragm. Histological examination revealed a benign meningothelial meningioma. Six months later, she complained of heaviness of her head and a head CT scan revealed an intracranial mass. A craniotomy was performed and a brain tumor was found to be histologically identical to the lung tumors. During the 21 years since the first operation, we performed three times of pulmonary and pleural metastasectomies and two times of resection of intracranial local recurrences. All of those tumors were meningothelial meningioma without malignant change. The patient is alive without metastasis after the last resection of metastatic tumors.
脑膜瘤通常为良性肿瘤，但很少会转移至中枢神经系统以外。一名25岁女性因胸部X光片出现异常阴影而入住我院。计算机断层扫描（CT）显示右肺下叶有一个3厘米、边界清晰的肿块。我们进行了开胸手术，切除了右肺和膈肌的三个肺部肿瘤。组织学检查显示为良性脑膜内皮型脑膜瘤。六个月后，她主诉头部沉重，头部CT扫描发现颅内有肿块。进行了开颅手术，发现脑部肿瘤在组织学上与肺部肿瘤相同。自首次手术以来的21年里，我们进行了三次肺和胸膜转移瘤切除术以及两次颅内局部复发肿瘤切除术。所有这些肿瘤均为脑膜内皮型脑膜瘤，无恶变。在最后一次切除转移瘤后，患者存活且无转移。
