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复发性脑膜瘤伴肺转移的恶性转化

Malignant transformation of recurrent meningioma with pulmonary metastases.

作者信息

LeMay D R, Bucci M N, Farhat S M

机构信息

Department of Surgery, University of Michigan.

出版信息

Surg Neurol. 1989 May;31(5):365-8. doi: 10.1016/0090-3019(89)90068-2.

DOI:10.1016/0090-3019(89)90068-2
PMID:2711310
Abstract

A patient presented with a histologically benign intracranial meningioma which, after multiple recurrences, underwent malignant transformation. The patient survived 18 years following initial presentation. Pulmonary metastases were present over the final 8 years. Eleven subtotal resections of the meningioma were performed, including exenteration of the right eye and a thoracotomy. Radiation therapy and chemotherapy were relatively ineffective. The problem and treatment of recurrent meningiomas is briefly reviewed.

摘要

一名患者最初被诊断为组织学上良性的颅内脑膜瘤,在多次复发后发生了恶性转化。该患者在首次就诊后存活了18年。在最后8年出现了肺转移。对脑膜瘤进行了11次次全切除,包括右眼摘除术和开胸手术。放疗和化疗效果相对不佳。本文简要回顾了复发性脑膜瘤的问题及治疗方法。

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