Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea.
Eur Neurol. 2013;69(4):236-41. doi: 10.1159/000345271. Epub 2013 Jan 25.
Little is known about optic radiation (OR) injury in intracerebral hemorrhage (ICH). We attempted to investigate OR injury in patients with ICH by diffusion tensor imaging (DTI).
Forty-three consecutive patients with putaminal hemorrhage and 40 normal healthy control subjects were recruited. DTI data were acquired at the beginning of rehabilitation (average 34 days after onset). DTI-Studio software was used to reconstruct the OR. Fractional anisotropies (FA) and fiber numbers of the ORs were measured. FA values and fiber numbers of affected ORs were described as abnormal when they were more than 2.5 SD lower than those of normal controls.
Thirty (70%) of the 43 patients showed an OR abnormality in the affected hemisphere. In 13 (30%) patients, the affected OR was disrupted or nonreconstructable. On the other hand, of the 20 patients with preserved OR integrity, 14 (33%) had a low FA value and 3 (7%) a low FA and fiber number. The other 13 (30%) of the 43 patients had no abnormal OR findings.
Seventy percent of patients showed any abnormality of OR in the affected hemisphere on DTI. This result suggests that patients with putaminal hemorrhage are at high risk of OR injury.
关于脑出血（ICH）患者的视辐射（OR）损伤知之甚少。我们试图通过弥散张量成像（DTI）来研究 ICH 患者的 OR 损伤。
共纳入 43 例壳核出血患者和 40 名正常健康对照者。DTI 数据在康复开始时采集（平均发病后 34 天）。使用 DTI-Studio 软件重建 OR。测量 OR 的各向异性分数（FA）和纤维数量。当受累 OR 的 FA 值和纤维数量比正常对照组低 2.5 个标准差以上时，描述为异常。
43 例患者中有 30 例（70%）在受累半球出现 OR 异常。在 13 例（30%）患者中，受累 OR 中断或无法重建。另一方面，在 20 例 OR 完整的患者中，14 例（33%）FA 值较低，3 例（7%）FA 值和纤维数量较低。43 例患者中的其他 13 例（30%）未发现异常 OR 表现。
70%的患者在 DTI 上受累半球的 OR 出现任何异常。这一结果提示壳核出血患者存在较高的 OR 损伤风险。
