Mason Molly A, Weant Kyle A, Baker Stephanie N
Department of Pharmacy Services, Indiana University Health Methodist Hospital, Indianapolis, IN 46202, USA.
Adv Emerg Nurs J. 2013 Jan-Mar;35(1):16-25; quiz 26-7. doi: 10.1097/TME.0b013e31827fb706.
Rapid sequence intubation is a stepwise process developed to assist health care providers in placing emergent artificial airways for patients requiring assisted ventilation. This practice includes routine administration of sedative and neuromuscular blocking agent (NMBA) medications for patient comfort during endotracheal tube placement. Members of the multidisciplinary team should be well educated about the various medications used during this process to ensure safe medication practices in an emergent situation. Recent drug shortages have forced many health care professionals to use alternative medications with which they are less familiar. The intent of this review is to familiarize health care providers with the pharmacology and adverse effect profiles of alternative sedative and NMBA medications used in emergent airway placement in light of recent drug shortages.
快速顺序诱导插管是一个逐步进行的过程，旨在帮助医护人员为需要辅助通气的患者建立紧急人工气道。这种操作包括在放置气管内导管期间常规给予镇静剂和神经肌肉阻滞剂（NMBA）药物，以提高患者舒适度。多学科团队成员应接受关于此过程中使用的各种药物的良好教育，以确保在紧急情况下安全用药。近期的药品短缺迫使许多医护人员使用他们不太熟悉的替代药物。本综述的目的是鉴于近期药品短缺的情况，使医护人员熟悉用于紧急气道放置的替代镇静剂和NMBA药物的药理学和不良反应情况。
