Peters C A, Bauer S B
Department of Surgery, Children's Hospital, Boston, Massachusetts.
Urol Clin North Am. 1990 May;17(2):379-87.
Posterior urethral valves lead to an overlapping constellation of urodynamic abnormalities, often many years after the initial diagnosis and valve ablation. Voiding dysfunction and urinary incontinence in boys with a history of valves are seldom the result of sphincteric incompetence. Three major categories of bladder dysfunction may cause voiding symptoms: myogenic failure, detrusor hyperreflexia, and bladder hypertonia. The interaction of the severity and duration of valve obstruction may be important factors, but the determinants of ultimate bladder function in the setting of urethral valves remain unclear. A careful urodynamic assessment is needed to define the abnormal bladder and to select and evaluate therapy. Therapy should be designed to provide low-pressure urinary storage for a socially acceptable period of time as well as complete emptying of the bladder. Success may require several lines of treatment and demands patience, not only of the patient and his family, but of the physician.
后尿道瓣膜会导致一系列重叠的尿动力学异常,通常在初始诊断和瓣膜切除多年后出现。有瓣膜病史的男孩出现排尿功能障碍和尿失禁很少是由于括约肌功能不全所致。膀胱功能障碍主要有三大类可导致排尿症状:肌源性衰竭、逼尿肌反射亢进和膀胱张力过高。瓣膜梗阻的严重程度和持续时间之间的相互作用可能是重要因素,但在存在尿道瓣膜的情况下,最终膀胱功能的决定因素仍不清楚。需要进行仔细的尿动力学评估,以明确膀胱异常情况,并选择和评估治疗方案。治疗方案应设计为在社会可接受的时间段内实现低压储尿以及膀胱完全排空。成功可能需要多种治疗方法,不仅需要患者及其家人有耐心,医生也需要有耐心。