Holmdahl G, Sillén U, Hanson E, Hermansson G, Hjälmås K
Department of Pediatric Surgery, Children's Hospital, Göteborg, Sweden.
J Urol. 1996 Feb;155(2):694-8.
We characterized bladder dysfunction in boys with posterior urethral valves during childhood and adolescence.
A total of 12 prepubertal boys with posterior urethral valves presenting before age 1 year was followed from ages 4 to 14 years and compared to 6 postpubertal boys with posterior urethral valves. Urodynamic evaluations and renal function studies were performed repeatedly.
Patients had a changing urodynamic pattern with instability decreasing with time, increasing bladder capacity and commonly an unsustained voiding contraction causing emptying difficulties. Postpubertal boys had high capacity bladders with low contractility.
We suggest that previously described urodynamic patterns of the valve bladder (unstable, poorly compliant and over distended bladders) are variations of the same basic pattern that changes with time toward decompensation.
我们对患有后尿道瓣膜的男孩在儿童期和青春期的膀胱功能障碍进行了特征描述。
对12名1岁前出现后尿道瓣膜的青春期前男孩进行了4至14岁的随访,并与6名青春期后患有后尿道瓣膜的男孩进行了比较。反复进行尿动力学评估和肾功能研究。
患者的尿动力学模式不断变化,不稳定性随时间降低,膀胱容量增加,且通常存在无法持续的排尿收缩,导致排空困难。青春期后男孩的膀胱容量大但收缩力低。
我们认为,先前描述的瓣膜膀胱尿动力学模式(不稳定、顺应性差和膀胱过度扩张)是同一基本模式的变体,该模式会随着时间向失代偿方向变化。