Greco A, Lanatà A, Valenza G, Rota G, Vanello N, Scilingo E P
Department of Information Engineering and Interdepartmental Research Center E. Piaggio, Faculty of Engineering, University of Pisa, Pisa, Italy.
Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:6691-4. doi: 10.1109/EMBC.2012.6347529.
People affected by bipolar disorders experience alternating states of depression with episodes of mania or hypomania. This mental can lead to a poor handling of daily routines, can worsen personal relationships, and often can be life-threatening. This preliminary study aims at investigating how the autonomic nervous system, in terms of electrodermal activity, responds to specific controlled emotional stimuli in bipolar patients. More specifically, we present here a method to deploy the analysis of ElectroDermal Activity (EDA) to discriminate clinical mood states. EDA was analyzed by using a deconvolution method to separate tonic from phasic components. The three subjects recruited and the experimental protocol used here is part of the European project PSYCHE. Preliminary results show that the bipolar mood states can be related to electrodermal tonic activity.
双相情感障碍患者会经历抑郁状态与躁狂或轻躁狂发作的交替。这种精神状况会导致日常事务处理不善，使人际关系恶化，而且常常会危及生命。这项初步研究旨在调查自主神经系统在皮肤电活动方面如何应对双相情感障碍患者特定的受控情绪刺激。更具体地说，我们在此提出一种运用皮肤电活动（EDA）分析来区分临床情绪状态的方法。通过去卷积方法分析EDA，以将紧张性成分与相位性成分分离。这里招募的三名受试者以及所采用的实验方案是欧洲项目PSYCHE的一部分。初步结果表明，双相情感障碍的情绪状态可能与皮肤电紧张性活动有关。
