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[幽门螺杆菌及其检测与胃十二指肠常见病理状况的关联]

[Campylobacter pylori, its detection and association with common pathologic conditions of the gastro-duodenum].

作者信息

Fixa B, Komárková O, Krejsek J, Bures J, Melichar B, Dvorácek I

机构信息

II. interní klinika Fakultní nemocnice, Hradec Králové.

出版信息

Vnitr Lek. 1990 Feb;36(2):170-6.

PMID:2336815
Abstract

The authors evaluate clinical experience based on a correlation between the clinical condition and the finding of Campylobacter pylori (CP) in a total of 1027 specimens of the gastric mucosa. They confirmed the high incidence of CP in patients with a fresh duodenal ulcer (g 7%) but also in the inactive stage of duodenal ulcer disease (97.8%) and in patients with a pyloric ulcer (94.4%). An analogous incidence of CP in patients with so-called isolated duodenitis (in the course of the disease no ulcer lesion was ever detected), i.e. in 95.5%, indicates the relationship of this condition with peptic ulcer disease. The authors indicate diagnostic possibilities as regards CP infection by cultivation, rapid urease tests and microscopic examination and they emphasize the practical value of urease tests. Based on their own experience the authors confirm the high eradication effect of bismuth preparations, in particular bismuth subsalicylate and colloid bismuth subcitrate.

摘要

作者基于临床状况与1027份胃黏膜标本中幽门弯曲菌(CP)检测结果之间的相关性评估临床经验。他们证实,新鲜十二指肠溃疡患者中CP的发病率很高(7%),十二指肠溃疡病非活动期患者中CP发病率也很高(97.8%),幽门溃疡患者中CP发病率同样很高(94.4%)。在所谓的孤立性十二指肠炎患者(病程中从未检测到溃疡病变)中,CP的发病率类似,为95.5%,这表明该病症与消化性溃疡病之间存在关联。作者指出了通过培养、快速尿素酶试验和显微镜检查诊断CP感染的可能性,并强调了尿素酶试验的实用价值。基于自身经验,作者证实铋制剂,尤其是碱式水杨酸铋和枸橼酸铋钾,具有很高的根除效果。

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