Gullini S, Basso O, Boccia S, Macario F, Cantarini D, Ghinelli F
U.S.L. n. 31 - Arcispedale Sant'Anna - Ferrara.
Minerva Med. 1988 Nov;79(11):957-60.
355 patients suffering from dyspepsia with an endoscopic pathological picture were examined. Campylobacter pylori was sought histologically and by culture. Histological and cultural results were compared. There were no bacteria on the gastric mucosa of 46 patients who had no histopathological evidence of lesions. Cultural studies were performed in 40 cases on endoscopic instruments used during the examination, before and after standard sterilization. Campylobacter pylori was found on the gastric mucosa of 224 patients (63.09%); 91.93% with duodenal ulcer; 71.87% with gastric ulcer; 54.23% with erosive duodenitis; 56.71% with erosive gastritis and 54.81% with chronic gastropathy. The agreement between the two techniques was 75.39%, with a male prevalence (p = 0.05). Campylobacter pylori was present on the gastric mucosa of 10.86% of patients without histopathological evidence of lesions. Standard sterilization with alkyl-dimethyl-benzyl ammonium eliminated the campylobacter in 100% of cases.
对355例有内镜病理图像的消化不良患者进行了检查。通过组织学检查和培养来寻找幽门螺杆菌。比较了组织学和培养结果。46例无组织病理学病变证据的患者胃黏膜上未发现细菌。对40例检查过程中使用的内镜器械在标准灭菌前后进行了培养研究。224例患者（63.09%）的胃黏膜上发现了幽门螺杆菌；十二指肠溃疡患者中占91.93%；胃溃疡患者中占71.87%；糜烂性十二指肠炎患者中占54.23%；糜烂性胃炎患者中占56.71%；慢性胃炎患者中占54.81%。两种技术之间的一致性为75.39%，男性患病率较高（p = 0.05）。10.86%无组织病理学病变证据的患者胃黏膜上存在幽门螺杆菌。用烷基二甲基苄基氯化铵进行标准灭菌在100%的病例中消除了弯曲杆菌。
