ICAP-Columbia University, Mailman School of Public Health, New York, NY 10032, USA.
Curr HIV/AIDS Rep. 2013 Jun;10(2):152-8. doi: 10.1007/s11904-013-0152-1.
In the past several years, the debate of "treatment vs prevention" has shifted with the introduction of the concept of "treatment as prevention," (TasP), stemming from a series of compelling observational, ecological, and modeling studies as well as HPTN 052, a randomized clinical trial, demonstrating that use of ART is associated with a decrease in HIV transmission. In addition to TasP being viewed as 1 intervention in a combination strategy for HIV Prevention, TasP is, in and of itself, a combination of multiple interventions that need to be implemented with high coverage in order to achieve its potential impact.
在过去的几年中,随着“治疗即预防”(TasP)概念的引入,“治疗与预防”的争论发生了转变,这一概念源自一系列引人注目的观察性、生态学和建模研究,以及 HPTN 052 随机临床试验,该试验表明抗逆转录病毒疗法的使用与艾滋病毒传播的减少有关。除了 TasP 被视为艾滋病毒预防综合战略中的一项干预措施之外,TasP 本身就是多种干预措施的组合,需要高覆盖率才能实现其潜在影响。