膀胱癌患者的生存分析，生命表法。
Survival analysis of patients with bladder cancer, life table approach.
作者信息
Rezaianzadeh Abbas, Mohammadbeigi Abolfazl, Mobaleghi Jafar, Mohammadsalehi Narges
机构信息
Research Center for Health Sciences, Department of Epidemiology, School of Health and Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
J Midlife Health. 2012 Jul;3(2):88-92. doi: 10.4103/0976-7800.104468.
BACKGROUND
Bladder cancer is the fourth most common malignancy in men and the eighth most common in women. It causes 8% of all malignancies in men and 3% of all malignancies in women. The trend of bladder cancer is increasing in Iran. This study was conducted to estimate the survival rate of bladder cancer based on life table method.
MATERIALS AND METHODS
In this study, at first, data were collected based on individual variables of 514 patients suffering from bladder cancer and referred them to cancer registry center of Shiraz University of Medical Sciences from 2001-2009. Data were collected at two stages and analyzed by life table method and Wilcox on test. Significant level considered at 0.05.
RESULTS
Our findings showed that probability of survival accumulation at the end of 1, 3, 5, 10 years in patients with bladder cancer were equal to 0.8989, 0.7132, 0.5752 and 0.2459 respectively. There was significant difference in survival rate among age groups and treatment types (P < 0.05). However, we did not observe any difference in survival time based on smoking (P = 0.578), alcohol (P = 0.419) and education level (P = 0.371) of patients.
CONCLUSION
The overall survival rate of bladder cancer in the present study was less than other areas. Patients' age and treatment type were the influential factor in survival time. So continuous screening for early diagnosis suggested for older people.
背景
膀胱癌是男性中第四大常见恶性肿瘤，女性中第八大常见恶性肿瘤。它导致男性所有恶性肿瘤的8%，女性所有恶性肿瘤的3%。伊朗膀胱癌的发病趋势正在上升。本研究旨在基于生命表法估计膀胱癌的生存率。
材料与方法
在本研究中，首先，收集了2001年至2009年期间514例膀胱癌患者的个体变量数据，并将他们转诊至设拉子医科大学癌症登记中心。数据分两个阶段收集，并通过生命表法和Wilcoxon检验进行分析。显著性水平设定为0.05。
结果
我们的研究结果表明，膀胱癌患者在1年、3年、5年、10年末的生存累积概率分别为0.8989、0.7132、0.5752和0.2459。年龄组和治疗类型之间的生存率存在显著差异（P < 0.05）。然而，我们未观察到患者的吸烟情况（P = 0.578）、饮酒情况（P = 0.419）和教育水平（P = 0.371）对生存时间有任何差异。
结论
本研究中膀胱癌的总体生存率低于其他地区。患者的年龄和治疗类型是生存时间的影响因素。因此建议对老年人进行持续筛查以早期诊断。
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