[The pathological anatomy of pneumococcal meningoencephalitis in adults].

The results of the clinico-morphological examination of the bacteriologically confirmed meningoencephalitis in 12 autopsy cases are presented. The gravity of the clinical course of the pneumococcus meningoencephalitis is due to infectious-toxic shock the main morphological manifestation of which is disseminated intravascular coagulation. Neurotoxicosis symptoms prevailed in the clinical picture of the infectious-toxic shock even though the morphological changes characteristic of shock were found in the brain as well as in the internal organs particularly in the adrenals, lungs and kidneys. The peculiar feature of the disseminated intravascular coagulation was the domination of the hypercoagulation stage with the variety of intravascular fibrin formations (fibrin, hyaline, globular thrombi, prethrombi, fibrinous threads).