Anisimova Iu N, Barshteĭn Iu A, Kuz'minskiĭ N P
Arkh Patol. 1985;47(12):61-4.
Clinico-morphological data on a severe course of salmonellosis (Stenley Salmonella) with the development of the infectious-toxic shock are presented. The shock was manifested by changes of the microcirculatory bed with the development of disseminated intra vascular blood coagulation (DIBC), brain and lung oedema as well as degenerative and necrobiotic lesions of the inner organs (acute tubular renal necrosis, necrobiosis and necrosis of the gastrointestinal tract epithelium, necrobiotic processes in the adrenal parenchyma, neuronal lysis etc.) as a consequence of circulatory disturbances determining the severity of the course and outcome of the disease. The possibility of a protracted course of the DIBS-syndrome as the main component of the infectious-toxic shock is shown and pathogenetically grounded.
本文介绍了沙门氏菌病（斯坦利沙门氏菌）严重病程伴发感染性中毒性休克的临床形态学数据。休克表现为微循环床改变，伴发弥散性血管内凝血（DIBC）、脑和肺水肿，以及由于循环障碍导致的内脏退行性和坏死性病变（急性肾小管坏死、胃肠道上皮坏死和坏死、肾上腺实质坏死过程、神经元溶解等），这些循环障碍决定了疾病的病程严重程度和预后。文中展示并从发病机制上阐述了DIBS综合征作为感染性中毒性休克主要组成部分出现迁延病程的可能性。
