Burduk Paweł K, Seredyka-Burduk Małgorzata, Kaźmierczak Wojciech, Dalke Krzysztof, Marszałek Andrzej
Katedra i Klinika Otolaryngologii i Onkologii Laryngologicznej Collegium Medium w Bydgoszczy, UMK w Toruniu, ul. Skłodowskiej-Curie 9, 85-094 Bydgoszcz, Poland.
Otolaryngol Pol. 2013 Jan-Feb;67(1):52-6. doi: 10.1016/j.otpol.2012.05.006. Epub 2012 May 7.
The benign lesions of the lacrimal sac are very rare. The most typical epithelial tumor is squamous papilloma. This tumors often present with symptoms of dacryostenosis and dacriocystitis. Human papillomavirus (HPV) infection is known to be causative agent in the development of epithelial tumor. Lacrimal sac tumors could transform to malignant neoplasms, especially if they are developed of coexisting HPV infection. We present a patient with a squamous papilloma of the lacrimal sac and discussed the method of treatment. The patient was suffered from epiphora and recurrent dacriocystitis. An endoscopic surgery with dacriocystorhinostomy and local resection of the tumor could be an effective method of choice. The usage of a shaver for wide removal of the lacrimal sac wall is recommended to prevent local recurrence. The histopathology examination showed squamous papilloma. The patient is free of the disease over 8 months of follow up. Primary lacrimal sac papilloma require long term follow up for recurrence or malignant transformation. HPV infection could be associated with the development of lacrimal sac papillomas.
泪囊良性病变非常罕见。最典型的上皮性肿瘤是鳞状乳头状瘤。这种肿瘤常表现为泪道狭窄和泪囊炎的症状。已知人乳头瘤病毒(HPV)感染是上皮性肿瘤发生的致病因素。泪囊肿瘤可能会转变为恶性肿瘤,尤其是在存在HPV感染的情况下发生的肿瘤。我们报告了一例泪囊鳞状乳头状瘤患者,并讨论了治疗方法。该患者患有溢泪和复发性泪囊炎。内镜下泪囊鼻腔吻合术联合肿瘤局部切除术可能是一种有效的选择方法。建议使用刨削器广泛切除泪囊壁以防止局部复发。组织病理学检查显示为鳞状乳头状瘤。随访8个月以上,患者无疾病复发。原发性泪囊乳头状瘤需要长期随访以观察复发或恶变情况。HPV感染可能与泪囊乳头状瘤的发生有关。