Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, India.
Asian Pac J Trop Med. 2013 Mar;6(3):249-50. doi: 10.1016/S1995-7645(13)60034-6.
Leishmaniasis affects both the visceral and cutaneous tissues in body. Oral Mucosal involvement in leishmaniasis is rare and is often overlooked. We present a case 17 year old boy from the north east region of Bihar who has a history of visceral leishmaniasis one year back, came to the department of oral surgery for treatment of persistent oral ulcers. Oral examination did not give any diagnostic information while systemic examination revealed enlarged spleen and low grade fever. Patient was screened for leishmaniasis by rK39 based immunochromatographic strip test which came to be positive. Biopsy of the ulcer as well as splenic and bone marrow aspirate confirmed the presence of leishmaniasis. Patient was administered Amphotericin B for 20 days following which significant clinical and haematological improvement followed.
利什曼病影响身体的内脏和皮肤组织。利什曼病的口腔黏膜受累很少见，且常被忽视。我们报告了一例来自比哈尔邦东北部的 17 岁男孩，他在一年前患有内脏利什曼病，因持续性口腔溃疡来到口腔外科就诊。口腔检查没有提供任何诊断信息，而全身检查显示脾脏肿大和低度发热。患者通过 rK39 基于免疫层析的条带试验进行了利什曼病筛查，结果呈阳性。溃疡以及脾和骨髓抽吸物的活检证实存在利什曼病。患者接受了 20 天的两性霉素 B 治疗，随后临床和血液学有了显著改善。
