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命令性幻听与精神病谱系障碍患者自杀观念的临床特征。

Command hallucinations and clinical characteristics of suicidality in patients with psychotic spectrum disorders.

机构信息

Alpert Medical School, Brown University, Providence, RI 02912, USA.

出版信息

Compr Psychiatry. 2013 Aug;54(6):611-7. doi: 10.1016/j.comppsych.2012.12.022. Epub 2013 Jan 31.

Abstract

BACKGROUND

Suicide is a leading cause of death among patients with psychotic illnesses. Several researchers have suggested that specific illness symptoms may better predict suicide risk. An ability to identify high-risk patients would aid clinicians in instituting risk-reduction measures to decrease suicidal behavior in this population.

METHODS

We examined the association between psychotic symptoms and suicidal behavior among 148 inpatients with psychosis using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), the Scale for the Assessment of Positive Symptoms, and the Positive and Negative Syndrome Scale. Measures of suicidality were obtained from risk assessment clinical data routinely collected during intake.

RESULTS

For individuals with a DSM-IV diagnosed psychotic spectrum disorder, 40% (n=57) endorsed suicidal ideation on admission and 23% (n=33) endorsed a recent suicide attempt. The presence of command auditory hallucinations was significantly associated with active suicidal ideation across diagnostic categories. Similarly, a greater percentage of patients endorsed a recent suicide attempt in the presence of command hallucinations. These correlations with CAH are noteworthy, as we found no significant difference in the prevalence of SI among those with and without general auditory hallucinations (42.5% and 37.7%).

CONCLUSIONS

The presence of command auditory hallucinations, in particular, but not auditory hallucinations, in general, was associated with suicidal behavior. These results indicate that command auditory hallucinations may identify or even place psychotic individuals at greater risk for acute, suicidal behavior--these symptoms should be the target of immediate and aggressive characterization and treatment.

摘要

背景

自杀是精神疾病患者的主要死亡原因之一。一些研究人员认为,特定的疾病症状可能更好地预测自杀风险。能够识别高风险患者将有助于临床医生采取减少自杀行为的措施,降低这一人群的自杀率。

方法

我们使用精神障碍诊断与统计手册第四版(DSM-IV)的诊断访谈表、阳性症状评定量表和正负症状量表,对 148 名精神病住院患者的精神病症状与自杀行为之间的关系进行了研究。自杀行为的测量来自于在入院时常规收集的风险评估临床数据。

结果

对于患有 DSM-IV 诊断为精神病谱系障碍的个体,40%(n=57)在入院时存在自杀意念,23%(n=33)在最近有过自杀企图。出现命令性幻听与各种诊断类别中的主动自杀意念显著相关。同样,在出现命令性幻听的情况下,更多的患者有过最近的自杀企图。这些与 CAH 的相关性值得注意,因为我们发现有和没有一般听觉幻觉的患者的 SI 患病率没有显著差异(42.5%和 37.7%)。

结论

特别是命令性幻听的存在,而不是一般性听觉幻觉的存在,与自杀行为有关。这些结果表明,命令性幻听可能会识别甚至使精神病患者面临更大的急性自杀风险——这些症状应成为立即和积极描述和治疗的目标。

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