Hume W J, Moore J K, Main D M
Department of Dental Surgery, University of Leeds School of Dentistry.
Br J Oral Maxillofac Surg. 1990 Apr;28(2):85-8. doi: 10.1016/0266-4356(90)90127-7.
Ninety-three odontogenic cysts, 42 of inflammatory and 51 of developmental origin, were grown in vitro from explants and/or cell suspensions. There was little difference in the success rate of culturing epithelium from explants of dentigerous cysts (N = 28) or odontogenic keratocysts (N = 23) (approximately 75% and 87%, respectively) and the dentigerous cyst grew particularly well from suspensions (N = 11) (91%) compared with the keratocyst (N = 19) (58%). Epithelium from developmental odontogenic cysts grew much better in vitro than did cysts of inflammatory origin (56 to 58% from explants and 19 to 25% from suspension). From this work there is little evidence to support previous statements that the dentigerous cyst cannot be grown from explants, or that the odontogenic keratocyst has 'aggressive' growth characteristics.
93个牙源性囊肿（42个炎症性起源，51个发育性起源）通过外植体和/或细胞悬液在体外培养。从含牙囊肿（N = 28）或牙源性角化囊肿（N = 23）的外植体培养上皮的成功率差异不大（分别约为75%和87%），与角化囊肿（N = 19）（58%）相比，含牙囊肿从悬液（N = 11）培养效果特别好（91%）。发育性牙源性囊肿的上皮在体外生长比炎症性起源的囊肿好得多（外植体培养为56%至58%，悬液培养为19%至25%）。从这项研究中，几乎没有证据支持之前关于含牙囊肿不能从外植体培养，或牙源性角化囊肿具有“侵袭性”生长特征的说法。
