Vissum Corporation, Alicante, Spain.
J Cataract Refract Surg. 2013 Apr;39(4):519-27. doi: 10.1016/j.jcrs.2012.10.045. Epub 2013 Feb 1.
To evaluate the clinical outcomes of laser in situ keratomileusis (LASIK) for high hyperopia using an excimer laser and optimized aspheric profiles.
Vissum Corporation and Miguel Hernández University, Alicante, Spain, and Research Institute of Ophthalmology, Giza, Egypt.
Case series.
Eyes of patients with high hyperopia or hyperopic astigmatism (spherical equivalent [SE] ≥ 5.64 diopters [D]) had uneventful LASIK with an aspheric optimized ablation profile centered on the corneal vertex using an Amaris 500 kHz excimer laser and a femtosecond platform for flap creation with a temporal hinge.
There was a significant improvement in uncorrected distance visual acuity 3 months postoperatively (P<.01), with no significant changes afterward (P=.72). At 6 months, the corrected distance visual acuity (CDVA) remained unchanged or improved in 90.48% of eyes; 2 eyes (9.52%) lost 2 lines of logMAR CDVA. The postoperative SE was within ± 0.50 D of emmetropia in 70.37% of eyes. The LASIK enhancement rate at the end of the follow-up was 29.4%. Significant induction of corneal primary spherical aberration and coma was found with 6.0 mm pupils (P<.01). The safety index was 0.94 and the efficacy index, 0.85.
Laser in situ keratomileusis for high hyperopia using optimized aspheric profiles requires further improvement in terms of safety but was still an effective and a predictable procedure.
评估使用准分子激光和优化的非球面轮廓对高度远视进行激光原位角膜磨镶术（LASIK）的临床效果。
Vissum 公司和西班牙阿利坎特的 Miguel Hernández 大学，以及埃及吉萨的眼科研究所。
病例系列。
远视或远视散光患者（等效球镜 [SE] ≥ 5.64 屈光度 [D]）的眼部接受了非球面优化消融轮廓的 LASIK，该消融轮廓以角膜顶点为中心，使用 Amaris 500 kHz 准分子激光和飞秒平台进行瓣创建，瓣带有颞侧铰链。
术后 3 个月，未矫正远视力（UDVA）显著改善（P<.01），此后无明显变化（P=.72）。术后 6 个月，90.48%的眼睛的矫正远视力（CDVA）保持不变或改善；2 只眼睛（9.52%）失去 2 行 logMAR CDVA。术后 SE 在± 0.50 D 屈光度以内的眼睛占 70.37%。在随访结束时，LASIK 增强率为 29.4%。使用 6.0 mm 瞳孔时，发现角膜初级球差和彗差显著诱导（P<.01）。安全性指数为 0.94，有效性指数为 0.85。
使用优化非球面轮廓对高度远视进行 LASIK 需要进一步提高安全性，但仍然是一种有效且可预测的手术。
