Novartis Animal Health, Centre de Recherche Santé Animale SA, 1566St Aubin, Switzerland.
Trends Parasitol. 2013 Mar;29(3):129-34. doi: 10.1016/j.pt.2013.01.001. Epub 2013 Feb 1.
Anthelmintic treatment of nematode infections remains the mainstay of worm control in farm and companion animals. However, control is threatened by the occurrence of drug resistant nematodes. In recent years, three new anthelmintics have been introduced to the market. Here, we describe the main features including mode of action, availability, spectrum, dose, tolerability, safety, and resistance of emodepside, monepantel, and derquantel.
抗蠕虫药物治疗仍然是农场动物和伴侣动物蠕虫病防治的主要手段。然而,药物耐药性寄生虫的出现对控制构成了威胁。近年来,三种新的驱虫药已投放市场。本文描述了其主要特点,包括作用模式、可及性、谱、剂量、耐受性、安全性和耐药性。