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采用口腔内骨移植物和生物材料对萎缩上颌骨进行整体重建:锥形束 CT 验证的前瞻性临床研究。

Total reconstruction of the atrophic maxilla with intraoral bone grafts and biomaterials: a prospective clinical study with cone beam computed tomography validation.

机构信息

Institute of Maxillofacial Surgery and Implantology, Teknon Medical Center, Barcelona, Spain.

出版信息

Int J Oral Maxillofac Implants. 2013 Jan-Feb;28(1):241-51. doi: 10.11607/jomi.2405.

Abstract

PURPOSE

To perform a preliminary validation with cone beam computed tomography (CBCT) of the combined use of intraoral bone blocks and biomaterials for total reconstruction of the atrophic maxilla.

MATERIALS AND METHODS

Consecutive cases of total edentulism of the maxilla (Cawood and Howell classes IV or V) treated with bilateral sinus floor elevation, mandibular bone block grafts, and biomaterials were evaluated prospectively. Implants were placed 14 to 16 weeks after grafting. Each patient received a CBCT scan preoperatively, immediately after bone augmentation, and at reentry. A three-dimensional reconstruction of the maxilla with volumetric calculations was obtained at each stage.

RESULTS

Fourteen patients participated. Successful graft integration occurred in all cases, with no major complications. Mean preoperative volume was 11,312 mm3. Mean postoperative volume was 19,997 mm3 immediately after surgery and 19,042 mm3 before implant insertion. The average percentage volumetric increase between the preoperative condition and the situation at reentry was 71.99%. One hundred eight implants were inserted. Immediate loading was possible with 81 implants in 10 patients.

CONCLUSIONS

The rehabilitation of the severely resorbed maxilla remains a formidable challenge. The results of this study suggest that the use of mandibular bone blocks in combination with biomaterials is an effective, reliable procedure for the rehabilitation of the severely resorbed maxilla. Significant volume increases and adequate stability of the augmented areas at reentry were found with CBCT analysis. The grafted bone provided sufficient mechanical support to permit provisionalization and immediate loading. This technique enabled the restoration of function and esthetics with a fixed rehabilitation at 4 months.

摘要

目的

通过锥形束 CT(CBCT)对使用口腔内骨块和生物材料联合进行全上颌骨萎缩重建进行初步验证。

材料和方法

前瞻性评估了连续接受双侧窦底提升、下颌骨骨块移植和生物材料治疗的全上颌无牙患者(Cawood 和 Howell 分类 IV 或 V)。种植体在移植后 14 至 16 周放置。每位患者在术前、骨增量后和再进入时均接受 CBCT 扫描。在每个阶段均获得了上颌骨的三维重建和体积计算。

结果

14 名患者参与了研究。所有病例均成功实现了骨移植整合,无重大并发症。术前平均体积为 11312mm³。术后即刻平均体积为 19997mm³,植入前为 19042mm³。术前至再进入时的平均体积增加百分比为 71.99%。共植入了 108 个种植体。10 名患者中有 81 个种植体可立即负重。

结论

严重萎缩上颌骨的修复仍然是一个艰巨的挑战。本研究结果表明,使用下颌骨骨块联合生物材料是一种有效、可靠的方法,可用于严重萎缩上颌骨的修复。CBCT 分析发现,增加的区域体积增加显著,并且在再进入时具有足够的稳定性。移植骨为临时修复和即刻负重提供了足够的机械支撑。该技术可在 4 个月内实现固定修复,恢复功能和美观。

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