Maxillo-facial Surgery Unit, San Filippo Neri Hospital, Rome, Italy.
Implant Dent. 2013 Feb;22(1):8-15. doi: 10.1097/ID.0b013e3182777239.
To report the histological outcomes of a case of bilateral severely resorbed posterior maxilla augmented with the use of blocks of enzymatically deantigenated equine bone.
In conjunction with bilateral sinus lifts, blocks of enzymatically deantigenated equine bone were used bilaterally to augment the severely atrophic maxilla of a patient seeking a fixed implant-supported prosthesis. After 8 months, bone core samples were obtained from the augmentation sites and implants were placed.
Six months after implant placement, the peri-implant bone levels were maintained. A prosthesis delivered 3 months after implant placement provided excellent rehabilitation. Histological analysis of the bone cores revealed that the graft material was still undergoing remodeling, with newly formed vital bone in all fields and osteoclasts included in the mineralized component.
The deantigenated equine bone was biocompatible and resorbed only minimally. This material seems to offer excellent potential for being incorporated in a procedure that increases the width of edentulous alveolar crests.
报告一例双侧严重吸收的上颌后牙区使用酶解去抗原马骨块进行骨增量的组织学结果。
在双侧窦提升术的同时，使用酶解去抗原马骨块双侧增加一位寻求固定种植体支持修复的严重萎缩上颌骨。8 个月后，从增量部位获得骨芯样本并植入种植体。
植入后 6 个月，种植体周围骨水平得到维持。植入后 3 个月，修复体提供了良好的修复效果。骨芯的组织学分析显示，移植物材料仍在进行改建，所有区域均有新形成的有活力的骨，矿化成分中包含破骨细胞。
去抗原马骨具有生物相容性，吸收很少。这种材料似乎具有良好的潜力，可用于增加无牙牙槽嵴宽度的手术。
