Department of Anesthesiology, University of Virginia, PO Box 800710, Charlottesville, VA, 22008-0710, USA,
Cardiovasc Intervent Radiol. 2013 Oct;36(5):1213-20. doi: 10.1007/s00270-013-0549-7. Epub 2013 Feb 2.
Ethanol is an effective ablative agent used for the treatment of certain solid organ tumors and vascular malformations (VMs). The egress of ethanol beyond the target tissue can be associated with significant changes to the cardiopulmonary system that can lead to cardiac arrest. This article reviews the contemporary role of ethanol in tumor and VM treatment and discusses the physiological mechanisms of acute pulmonary hypertension and cardiovascular collapse. The importance of periprocedural recognition of the hemodynamic changes that can occur with the use of ethanol and the treatment of this condition are discussed.
乙醇是一种有效的消融剂，用于治疗某些实体器官肿瘤和血管畸形（VMs）。乙醇超出目标组织的逸出可能与心肺系统的重大变化有关，从而导致心脏骤停。本文回顾了乙醇在肿瘤和 VM 治疗中的当代作用，并讨论了急性肺动脉高压和心血管崩溃的生理机制。讨论了在使用乙醇时可能发生的血流动力学变化的围手术期识别和治疗的重要性。
