Department of Lung Function and Sleep, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Mindelsohn Way, Edgbaston, Birmingham, B15 2WB, UK.
Drugs Aging. 2013 Apr;30(4):215-25. doi: 10.1007/s40266-013-0053-4.
The prevalence of chronic obstructive pulmonary disease (COPD) increases with age. Recent evidence suggests that the finding of co-existent bronchiectasis is becoming increasingly common, possibly because of increased use of high-resolution CT scanning in the assessment of patients with COPD. This may represent a distinct phenotype of COPD, but, nevertheless, it is likely to pose an increased burden to health services and challenges in determining the correct management of these patients. Here, we review the factors associated with bronchiectasis in older patients with COPD and the evidence for many of the therapies currently used in the treatment of patients, providing a rational approach to their management.
慢性阻塞性肺疾病(COPD)的患病率随着年龄的增长而增加。最近的证据表明,共存支气管扩张的发现变得越来越常见,可能是因为在 COPD 患者的评估中越来越多地使用高分辨率 CT 扫描。这可能代表 COPD 的一种独特表型,但无论如何,它可能会给卫生服务带来更大的负担,并在确定这些患者的正确治疗方法方面带来挑战。在这里,我们回顾了与老年 COPD 患者支气管扩张相关的因素,以及目前用于治疗患者的许多治疗方法的证据,为其治疗提供了一种合理的方法。