Jessamine P G, Brunham R C
Department of Medicine, University of Manitoba, Winnipeg.
CMAJ. 1990 May 15;142(10):1081-5.
From June to November 1987 an outbreak of chancroid occurred in Winnipeg, the first in more than 10 years; 14 people (9 men, 5 women) were involved. Nine of the cases were confirmed through culture. A control strategy was implemented in November 1987 that included presumptive treatment of genital ulcer disease with single-dose antimicrobial therapy, intensive tracing of contacts and treatment of asymptomatic sexual contacts. The origin of the outbreak was not determined, and an epidemiologic link between all the patients could not be demonstrated. The isolates were found to contain the same plasmid; this suggested that a single clone of Haemophilus ducreyi was responsible for the outbreak.
1987年6月至11月,温尼伯市爆发了软下疳,这是10多年来的首次;涉及14人(9名男性,5名女性)。其中9例通过培养确诊。1987年11月实施了一项控制策略,包括用单剂量抗菌疗法对生殖器溃疡疾病进行推定治疗、对接触者进行强化追踪以及对无症状性接触者进行治疗。此次疫情的源头未查明,且无法证明所有患者之间存在流行病学关联。分离株被发现含有相同的质粒;这表明单一克隆的杜克雷嗜血杆菌是此次疫情的病因。