Unit of Periodontology, Centre of Oral Health, University of Greifswald, Greifswald, Germany.
J Clin Periodontol. 2013 Mar;40(3):203-11. doi: 10.1111/jcpe.12056.
To examine the associations between factors of socio-economic status (SES), systemic inflammation and the progression of periodontitis and incidence of tooth loss.
Data of 2566 participants from the Study of Health in Pomerania (SHIP) with a 5-year follow-up were analysed. We evaluated attachment loss and tooth loss with regard to social variables including education, income, marital status and related risks such as smoking and obesity.
Socio-economic factors were associated with the progression of attachment level and tooth loss during the follow-up period. Low education and low income were associated with tooth loss (incidence risk ratio IRR 1.63, p < 0.001 and 1.25, p < 0.001 respectively) and also progression of mean clinical attachment level (p < 0.010 and p = 0.046 respectively). SES as well as smoking and obesity were also associated with increased levels of C-reactive protein (CRP) with effect modifications between SES factors and CRP, also between gender and marital status. Tooth loss was associated with disadvantageous SES, particularly under conditions of high CRP levels (p < 0.001).
The progression of periodontal disease is influenced by socio-economic factors. Effect modifications of socio-behavioural factors by CRP indicate that under conditions of systemic inflammation adverse SES effects may be aggravated.
探讨社会经济地位（SES）因素、全身炎症与牙周炎进展和牙齿丧失的关系。
对来自波罗的海健康研究（SHIP）的 2566 名参与者进行了为期 5 年的随访，对附着丧失和牙齿缺失与包括教育、收入、婚姻状况在内的社会变量以及吸烟和肥胖等相关风险进行了评估。
SES 因素与随访期间附着水平和牙齿丧失的进展有关。低教育和低收入与牙齿缺失（发病率风险比 IRR 分别为 1.63，p<0.001 和 1.25，p<0.001）和平均临床附着水平的进展（p<0.010 和 p=0.046）有关。SES 以及吸烟和肥胖也与 C 反应蛋白（CRP）水平升高有关，SES 因素与 CRP 之间以及性别与婚姻状况之间存在交互作用。牙齿缺失与 SES 不利有关，特别是在 CRP 水平较高的情况下（p<0.001）。
牙周病的进展受社会经济因素的影响。SES 因素对 CRP 的行为因素的修饰表明，在全身炎症的情况下，SES 不利的影响可能会加剧。
Zotero 插件