利用税收差异估算饮酒对无牙状态的影响。
Capitalising on Tax Variation to Estimate the Effect of Alcohol Consumption on Edentulism.
作者信息
Baumeister Sebastian-Edgar, Holtfreter Birte, Kocher Thomas, Nascimento Gustavo G
机构信息
Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany.
Department of Restorative Dentistry, Periodontology and Endodontology, University Medicine Greifswald, Greifswald, Germany.
出版信息
J Clin Periodontol. 2025 Aug;52(8):1108-1114. doi: 10.1111/jcpe.14176. Epub 2025 May 6.
AIM
To estimate alcohol consumption's effect on edentulism using state alcohol taxes as an instrumental variable (IV).
MATERIAL AND METHODS
Analysis of 514,357 U.S. Behavioural Risk Factor Surveillance System participants (2003-2006, 2008, 2010, 2012) linked to state alcohol taxes. We used IV regression modelling to assess the relationship between alcohol consumption and edentulism, plus potential mediators (body mass index, dental visits) and a positive control (coronary heart disease). Robustness to imperfect exogeneity was evaluated through sensitivity analyses and falsification testing using IV analysis on individuals under the age of 16 years.
RESULTS
A 1.1-drink increment per day was associated with a 12% higher risk of edentulism (95% confidence interval: 9%-16%). Alcohol consumption was positively associated with body mass index, dental visits and coronary heart disease. No significant effect on edentulism was observed in the negative control population (individuals aged < 16 years).
CONCLUSION
The findings of this quasi-experimental study suggest that alcohol consumption increases the risk of edentulism.
目的
使用州酒精税作为工具变量（IV）来评估酒精消费对无牙症的影响。
材料与方法
对514357名与州酒精税相关的美国行为危险因素监测系统参与者（2003 - 2006年、2008年、2010年、2012年）进行分析。我们使用工具变量回归模型来评估酒精消费与无牙症之间的关系，以及潜在的中介因素（体重指数、看牙次数）和一个阳性对照（冠心病）。通过敏感性分析和对16岁以下个体使用工具变量分析进行证伪检验，评估对不完全外生性的稳健性。
结果
每天饮酒量增加1.1杯与无牙症风险增加12%相关（95%置信区间：9% - 16%）。酒精消费与体重指数、看牙次数和冠心病呈正相关。在阴性对照人群（年龄<16岁的个体）中未观察到对无牙症有显著影响。
结论
这项准实验研究的结果表明，酒精消费会增加无牙症的风险。
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