[恰帕斯州儿童的癌症]

[Cancer in children from Chiapas state].

作者信息

González-Miranda Guadalupe, Carreón-Cruz Rogelio, Fajardo-Gutiérrez Arturo

机构信息

Unidad de Investigación en Epidemiología Clinica, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2011;49 Suppl 1:S111-20.

PMID:23383480

Abstract

In Chiapas, a total of 209 new cases of childhood cancers were registered between 1996 and 2007. Of these cases, 60.3% were composed of leukemias (32.1%), central nervous system tumors (CNST, 18.2%), and lymphomas (10.0%). Chiapas had the highest frequency of retinoblastoma (Rb, 9.6%). Not only did Chiapas have the highest incidence of childhood cancers overall (174.2) (all rates per 1000 000 children/year), but also the highest incidences of CNST, Rb, germ cell tumors, and carcinomas (32.5, 21.4, 10.9, and 4.2, respectively). By age, the highest incidence was found for those less than five years of age. The male/female ratio was 1.1. The incidence showed a trends to decrease (average annual percent change -9.8; CI 95% -13.6, -5.8). Of children with solid tumors, 58.7 % had been diagnosed with either stage III or IV.

摘要

1996年至2007年间，恰帕斯州共登记了209例儿童癌症新病例。在这些病例中，60.3%由白血病（32.1%）、中枢神经系统肿瘤（CNST，18.2%）和淋巴瘤（10.0%）组成。恰帕斯州视网膜母细胞瘤（Rb，9.6%）的发病率最高。恰帕斯州不仅儿童癌症总体发病率最高（174.2）（所有发病率均为每100万儿童/年），而且CNST、Rb、生殖细胞肿瘤和癌的发病率也最高（分别为32.5、21.4、10.9和4.2）。按年龄划分，五岁以下儿童的发病率最高。男女比例为1.1。发病率呈下降趋势（平均年变化率-9.8；95%置信区间-13.6，-5.8）。在患有实体瘤的儿童中，58.7%被诊断为III期或IV期。