Yano T, Kawaguchi S, Higashi T, Araki K, Komatsu S, Ichikawa Y, Kaji M
First Department of Internal Medicine, Kurume University School of Medicine.
Kansenshogaku Zasshi. 1990 Feb;64(2):231-5. doi: 10.11150/kansenshogakuzasshi1970.64.231.
A 19-year-old young man was admitted to our hospital complaining of fever and general fatigue. There were infiltrative shadows and pleural effusions in the both lung fields. Mycoplasma pneumoniae infection was diagnosed because of the elevation of mycoplasma antibody titers in the serum and pleural fluid. There was no recovery in clinical symptoms in spite of the administration of the EM (1200 mg) and CLDM (1200 mg) combination chemotherapy. Three week after admission, a cavity-like shadow appeared in the lt. middle lung field on the chest X-ray film, suprative arthritis and penicillin resistant S. aureus by blood culture test were found. Mycoplasma pneumoniae infection followed by S. aureus bacteremia was diagnosed. After the administration of antibiotics (CTT, FMOX) the clinical symptoms and laboratory findings improved 2 month after admission. Clinical and basic studies about the dual infection between M. pneumoniae and several bacteria were discussed.
一名19岁的年轻男子因发热和全身乏力入院。双肺野有浸润性阴影和胸腔积液。血清和胸腔积液中支原体抗体滴度升高,诊断为肺炎支原体感染。尽管使用了EM(1200mg)和CLDM(1200mg)联合化疗,临床症状仍未缓解。入院三周后,胸部X线片显示左中肺野出现空洞样阴影,血培养发现化脓性关节炎和耐青霉素金黄色葡萄球菌。诊断为肺炎支原体感染后继发金黄色葡萄球菌菌血症。使用抗生素(CTT、FMOX)治疗后,入院2个月后临床症状和实验室检查结果有所改善。讨论了肺炎支原体与几种细菌双重感染的临床和基础研究。