Suzuyama Y, Iwasaki H, Izumikawa K, Hara K
Yale J Biol Med. 1983 Sep-Dec;56(5-6):487-91.
Although self-limited respiratory tract infections caused by Mycoplasma pneumoniae are well recognized in children and young adults, respiratory involvements and hepatic dysfunction may occur. The frequency and clinical features of these complications were investigated. Experimental studies with regard to bacterial superinfection were also carried out. The test animals which were first infected with Mycoplasma pneumoniae and then with Staphylococcus aureus showed more extensive bacteriological and pathological changes than those infected with Staphylococcus aureus only. Liver biopsies performed on three human patients showed hepatic dysfunction and the histological findings were diagnosed as non-specific reactive hepatitis in each case.
虽然肺炎支原体引起的自限性呼吸道感染在儿童和年轻人中已广为人知,但仍可能出现呼吸道受累及肝功能障碍。对这些并发症的发生率和临床特征进行了调查。还开展了关于细菌重叠感染的实验研究。先感染肺炎支原体再感染金黄色葡萄球菌的实验动物,比仅感染金黄色葡萄球菌的动物表现出更广泛的细菌学和病理学变化。对三名人类患者进行的肝活检显示肝功能障碍,组织学检查结果在每例中均诊断为非特异性反应性肝炎。