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FDG-PET/CT 上酷似转移病灶的食物残渣肉芽肿。

Food residue granuloma mimicking metastatic disease on FDG-PET/CT.

机构信息

Department of Surgery, Catholic University of the Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli 8, 00168 Rome, Italy.

出版信息

Jpn J Radiol. 2013 May;31(5):349-51. doi: 10.1007/s11604-013-0184-x. Epub 2013 Feb 6.

DOI:10.1007/s11604-013-0184-x
PMID:23385380
Abstract

A 31-year-old woman presenting with acute abdomen underwent an emergency Hartmann's procedure for fecal peritonitis due to perforated adenocarcinoma of the left colon. Shortly after a 7-month course of adjuvant chemotherapy, follow-up contrast-enhanced CT showed multiple peritoneal and hepatic nodules, showing focal intense and homogeneous FDG uptake on FDG-PET/CT, highly suspected for recurrence of disease. Excisional biopsy of the nodules revealed foreign body granulomas made up of alimentary materials surrounded by a fibrous wall. We report a unique case of a false-positive finding secondary to food residues mimicking metastatic disease on FDG-PET in a patient with colon cancer.

摘要

一位 31 岁女性因左结肠癌穿孔腺癌并发粪性腹膜炎行急症 Hartmann 手术。辅助化疗 7 个月后,行增强 CT 随访显示多发腹膜和肝结节,FDG-PET/CT 示结节局灶性摄取明显且均匀,高度怀疑疾病复发。结节切除活检显示异物肉芽肿,由纤维壁包围的食物残渣组成。我们报告 1 例结肠癌患者 FDG-PET 上因食物残渣导致的假阳性结果,类似转移性疾病。

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本文引用的文献

1
F-18 FDG PET of foreign body granuloma: pathologic correlation with imaging features in 3 cases.F-18 FDG PET 在外体性肉芽肿中的应用:3 例与影像学特征的病理相关性研究。
Clin Nucl Med. 2010 Nov;35(11):853-7. doi: 10.1097/RLU.0b013e3181f483da.
2
(18)F-DG PET/CT in detection of recurrence and metastasis of colorectal cancer.(18)氟代脱氧葡萄糖正电子发射断层显像/X线计算机体层成像(F-DG PET/CT)在结直肠癌复发和转移检测中的应用
World J Gastroenterol. 2007 Oct 7;13(37):5025-9. doi: 10.3748/wjg.v13.i37.5025.
3
Colorectal cancer presenting as surgical emergencies.
直肠癌手术后回肠造口关闭导致的缝线肉芽肿伴肾积水:一例报告
Surg Case Rep. 2021 Sep 18;7(1):210. doi: 10.1186/s40792-021-01303-7.
4
An FDG-PET/CT-positive lesion mimicking local recurrence of colon cancer 5 years after radical colectomy.一例在根治性结肠切除术后5年出现的FDG-PET/CT阳性病变,酷似结肠癌局部复发。
Am J Case Rep. 2015 Mar 12;16:149-52. doi: 10.12659/AJCR.891129.
表现为外科急症的结直肠癌。
Surg Oncol. 2004 Aug-Nov;13(2-3):149-57. doi: 10.1016/j.suronc.2004.08.002.
4
Pitfalls in oncologic diagnosis with FDG PET imaging: physiologic and benign variants.FDG PET成像在肿瘤诊断中的陷阱:生理变异和良性病变
Radiographics. 1999 Jan-Feb;19(1):61-77; quiz 150-1. doi: 10.1148/radiographics.19.1.g99ja0761.