艾地苯醌对Leber遗传性视神经病变的治疗效果持久性。 - Suppr

Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy.

作者信息

Klopstock T, Metz G, Yu-Wai-Man P, Büchner B, Gallenmüller C, Bailie M, Nwali N, Griffiths P G, von Livonius B, Reznicek L, Rouleau J, Coppard N, Meier T, Chinnery P F

出版信息

Brain. 2013 Feb;136(Pt 2):e230. doi: 10.1093/brain/aws279. Epub 2013 Feb 6.

DOI:10.1093/brain/aws279

PMID:23388409

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3572931/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2050/3572931/78781f6366ff/aws279f1p.jpg

相似文献

Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy.艾地苯醌对Leber遗传性视神经病变的治疗效果持久性。

Brain. 2013 Feb;136(Pt 2):e230. doi: 10.1093/brain/aws279. Epub 2013 Feb 6.

A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy.随机安慰剂对照试验伊地苯醌治疗莱伯遗传性视神经病变。

Brain. 2011 Sep;134(Pt 9):2677-86. doi: 10.1093/brain/awr170. Epub 2011 Jul 25.

Visual function in chronic Leber's hereditary optic neuropathy during idebenone treatment initiated 5 to 50 years after onset.发病后 5 至 50 年开始用艾地苯醌治疗莱伯遗传性视神经病变的慢性期的视觉功能。

Graefes Arch Clin Exp Ophthalmol. 2019 Dec;257(12):2751-2757. doi: 10.1007/s00417-019-04444-6. Epub 2019 Sep 3.

[Raxone in the Leber optical neuropathy: Parisian experience].[雷索纳治疗莱伯视神经病变：巴黎的经验]

J Fr Ophtalmol. 2019 Mar;42(3):269-275. doi: 10.1016/j.jfo.2018.06.010. Epub 2019 Feb 1.

Novel use of idebenone in Leber's hereditary optic neuropathy in Hong Kong.艾地苯醌在香港用于治疗Leber遗传性视神经病变的新用途。

Hong Kong Med J. 2014 Oct;20(5):451-4. doi: 10.12809/hkmj134085.

Real-World Clinical Experience With Idebenone in the Treatment of Leber Hereditary Optic Neuropathy.依地酸-beta-羟乙酯治疗莱伯遗传性视神经病变的真实世界临床经验。

J Neuroophthalmol. 2020 Dec;40(4):558-565. doi: 10.1097/WNO.0000000000001023.

Idebenone treatment in Leber's hereditary optic neuropathy.艾地苯醌治疗Leber遗传性视神经病变。

Brain. 2011 Sep;134(Pt 9):e188. doi: 10.1093/brain/awr180. Epub 2011 Aug 2.

Idebenone for Leber's hereditary optic neuropathy.艾地苯醌用于治疗Leber遗传性视神经病变。

Drugs Today (Barc). 2016 Mar;52(3):173-81. doi: 10.1358/dot.2016.52.3.2463564.

Idebenone vs. rAAV2-ND4 gene therapy in the treatment of Leber's hereditary optic neuropathy: An indirect comparison meta-analysis.艾地苯醌与rAAV2-ND4基因疗法治疗Leber遗传性视神经病变：间接比较的荟萃分析

Indian J Ophthalmol. 2025 May 1;73(5):656-664. doi: 10.4103/IJO.IJO_2898_23. Epub 2025 Apr 24.

Comparing EPI-743 treatment in siblings with Leber's hereditary optic neuropathy mt14484 mutation.比较EPI-743对患有Leber遗传性视神经病变mt14484突变的同胞兄妹的治疗效果。

Can J Ophthalmol. 2013 Oct;48(5):e130-3. doi: 10.1016/j.jcjo.2013.05.011.

引用本文的文献

Pathogenic synergy: dysfunctional mitochondria and neuroinflammation in neurodegenerative diseases associated with aging.致病性协同作用：衰老相关神经退行性疾病中的线粒体功能障碍与神经炎症

Front Aging. 2025 Aug 5;6:1615764. doi: 10.3389/fragi.2025.1615764. eCollection 2025.

Technological advances in the diagnosis and management of inherited optic neuropathies.遗传性视神经病变诊断与管理的技术进展

Front Neurol. 2025 Jul 25;16:1609033. doi: 10.3389/fneur.2025.1609033. eCollection 2025.

Therapies for Mitochondrial Disease: Past, Present, and Future.线粒体疾病的治疗：过去、现在与未来

J Inherit Metab Dis. 2025 Jul;48(4):e70065. doi: 10.1002/jimd.70065.

Isolated and Syndromic Genetic Optic Neuropathies: A Review of Genetic and Phenotypic Heterogeneity.孤立性和综合征性遗传性视神经病变：遗传与表型异质性综述

Int J Mol Sci. 2025 Apr 20;26(8):3892. doi: 10.3390/ijms26083892.

Indian J Ophthalmol. 2025 May 1;73(5):656-664. doi: 10.4103/IJO.IJO_2898_23. Epub 2025 Apr 24.

Leber Hereditary Optic Neuropathy With Magnetic Resonance Imaging Findings Suggestive of Optic Perineuritis and Optic Neuritis: A Diagnostic Challenge.伴有提示视神经周围炎和视神经炎的磁共振成像表现的Leber遗传性视神经病变：一项诊断挑战。

Cureus. 2025 Mar 11;17(3):e80439. doi: 10.7759/cureus.80439. eCollection 2025 Mar.

Leber's hereditary optic neuropathy and multiple sclerosis: overlap between mitochondrial disease and neuroinflammation.莱伯遗传性视神经病变与多发性硬化症：线粒体疾病与神经炎症之间的重叠

Front Neurol. 2025 Feb 18;16:1538358. doi: 10.3389/fneur.2025.1538358. eCollection 2025.

Ganglion Cell Complex Thickness and Visual Function in Chronic Leber Hereditary Optic Neuropathy.慢性莱伯遗传性视神经病变的神经节细胞复合体厚度与视觉功能

Invest Ophthalmol Vis Sci. 2024 Oct 1;65(12):4. doi: 10.1167/iovs.65.12.4.

Emerging Multi-omic Approaches to the Molecular Diagnosis of Mitochondrial Disease and Available Strategies for Treatment and Prevention.线粒体疾病分子诊断的新兴多组学方法及可用的治疗与预防策略

Curr Genomics. 2024;25(5):358-379. doi: 10.2174/0113892029308327240612110334. Epub 2024 Jun 14.

Mitochondria in Retinal Ganglion Cells: Unraveling the Metabolic Nexus and Oxidative Stress.视网膜神经节细胞中的线粒体：揭开代谢关联和氧化应激之谜。

Int J Mol Sci. 2024 Aug 7;25(16):8626. doi: 10.3390/ijms25168626.

本文引用的文献

Is Leber hereditary optic neuropathy treatable? Encouraging results with idebenone in both prospective and retrospective trials and an illustrative case.Leber 遗传性视神经病变是否可治疗？前瞻性和回顾性试验中艾地苯醌的结果令人鼓舞，并有一个说明性病例。

J Neuroophthalmol. 2012 Mar;32(1):54-7. doi: 10.1097/WNO.0b013e318241da45.

Idebenone treatment in Leber's hereditary optic neuropathy.艾地苯醌治疗Leber遗传性视神经病变。

Brain. 2011 Sep;134(Pt 9):e188. doi: 10.1093/brain/awr180. Epub 2011 Aug 2.

A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy.随机安慰剂对照试验伊地苯醌治疗莱伯遗传性视神经病变。

Brain. 2011 Sep;134(Pt 9):2677-86. doi: 10.1093/brain/awr170. Epub 2011 Jul 25.

NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels.依赖 NQO1 的艾地苯醌氧化还原循环：对细胞氧化还原电位和能量水平的影响。

PLoS One. 2011 Mar 31;6(3):e17963. doi: 10.1371/journal.pone.0017963.

[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy].[对艾地苯醌和多种维生素疗法治疗Leber遗传性视神经病变的反应]

Arch Soc Esp Oftalmol. 2007 Jun;82(6):377-80. doi: 10.4321/s0365-66912007000600012.

Leber's hereditary optic neuropathy (LHON/11778) with myoclonus: report of two cases.伴有肌阵挛的Leber遗传性视神经病变（LHON/11778）：两例报告。

J Neurol Neurosurg Psychiatry. 2001 Dec;71(6):813-6. doi: 10.1136/jnnp.71.6.813.

Do idebenone and vitamin therapy shorten the time to achieve visual recovery in Leber hereditary optic neuropathy?艾地苯醌和维生素疗法能否缩短Leber遗传性视神经病变患者实现视力恢复的时间？

J Neuroophthalmol. 2000 Sep;20(3):166-70. doi: 10.1097/00041327-200020030-00006.

Leber's Hereditary Optic Neuropathy (LHON) with 14484/ND6 mutation in a North African patient.一名北非患者患有14484/ND6突变的Leber遗传性视神经病变（LHON）。

J Neurol Sci. 1998 Oct 8;160(2):183-8. doi: 10.1016/s0022-510x(98)00239-1.

Leber hereditary optic neuropathy: respiratory chain dysfunction and degeneration of the optic nerve.Leber遗传性视神经病变：呼吸链功能障碍与视神经变性

Vision Res. 1998 May;38(10):1495-504. doi: 10.1016/s0042-6989(97)00444-6.

Clinical and brain bioenergetics improvement with idebenone in a patient with Leber's hereditary optic neuropathy: a clinical and 31P-MRS study.

J Neurol Sci. 1997 May 1;148(1):25-31. doi: 10.1016/s0022-510x(96)00311-5.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy.

作者信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献