Hosseinzadeh Massood, Shokripur Mansureh, Salahi Heshmatollah
Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran;
Iran J Med Sci. 2012 Dec;37(4):271-3.
Squamous cell carcinoma of the gallbladder is rare and constitutes only 0.5-3% of all malignancies of this organ. Most of the reported cases have had a component of adenocarcinoma. We report a 70-year-old man who presented with acute onset right upper quadrant pain. He operated on based on a presumptive diagnosis of acute cholecystitis according to clinical and ultrasonographic findings. Histopathological examination of the infiltrating mass of the gallbladder revealed well differentiated keratinized squamous cell carcinoma invading full wall thickness. Thorough evaluations revealed no other primary site for the tumor. Pure primary squamous cell carcinoma of the gallbladder is rarely reported. Clinicians and pathologists must be aware of its vague clinical presentations.
胆囊鳞状细胞癌很罕见，仅占该器官所有恶性肿瘤的0.5%-3%。大多数报道的病例都合并有腺癌成分。我们报告一例70岁男性，因急性右上腹疼痛就诊。根据临床和超声检查结果，他被初步诊断为急性胆囊炎并接受了手术。胆囊浸润性肿块的组织病理学检查显示为高分化角化型鳞状细胞癌，侵犯全层。全面评估未发现肿瘤的其他原发部位。胆囊纯原发性鳞状细胞癌鲜有报道。临床医生和病理医生必须意识到其模糊的临床表现。
